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SeDeM expert system a new innovator tool to develop pharmaceutical forms
TLDR
The use of the SeDeM system reduced the time of medicine’s development and therefore the cost of the activity, and only four formulas could be considered suitable for use as an orodispersible tablet and accomplishes all the pharmaceutical quality parameters.
DNA delivery via cationic solid lipid nanoparticles (SLNs).
The role of SeDeM for characterizing the active substance and polyvinyilpyrrolidone eliminating metastable forms in an oral lyophilizate—A preformulation study
TLDR
A preformulation study of an oral lyophilisate with cetirizine dihydrochloride (CTZ) as active ingredient, mannitol and PVP K30 as bulking agents is presented, showing an adequate stability behavior in solid form.
Topical Administration of Bosentan Prevents Retinal Neurodegeneration in Experimental Diabetes
TLDR
It is concluded that topical administration of bosentan was effective in preventing neurodegeneration in the diabetic retina and, therefore, could be a good candidate to be tested in clinical trials.
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