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Crel, the carbon catabolite repressor protein from Trichoderma reesei
In order to investigate the mechanism of carbon catabolite repression in the industrially important fungus Trichoderma reesei, degenerated PCR‐primers were designed to amplify a 0.7‐bp fragment ofExpand
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Chromatin-level regulation of biosynthetic gene clusters.
Loss-of-function Aspergillus nidulans CclA, a Bre2 ortholog involved in histone H3 lysine 4 methylation, activated the expression of cryptic secondary metabolite clusters in A. nidulans. One newExpand
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Carbon catabolite repression of xylanase I (xyn1) gene expression in Trichoderma reesei
The filamentous fungus Trichoderma reesei forms two specific, xylan‐inducible xylanases encoded by xyn1 and xyn2 to degrade the β‐1,4‐d‐xylan backbone of hemicelluloses. This enzyme system is formedExpand
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RcoA has pleiotropic effects on Aspergillus nidulans cellular development
Aspergillus nidulans rcoA encodes a member of the WD repeat family of proteins. The RcoA protein shares sequence similarity with other members of this protein family, including the SaccharomycesExpand
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Enhancement of SIV infection with soluble receptor molecules.
The CD4 receptor on human T cells has been shown to play an integral part in the human immunodeficiency virus type 1 (HIV-1) infection process. Recombinant soluble human CD4 (rCD4) was tested for itsExpand
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Nucleosome Positioning and Histone H3 Acetylation Are Independent Processes in the Aspergillus nidulans prnD-prnB Bidirectional Promoter
ABSTRACT In Aspergillus nidulans, proline can be used as a carbon and nitrogen source, and its metabolism requires the integration of three signals, including proline induction and nitrogen andExpand
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Transcriptome analysis of nitrate assimilation in Aspergillus nidulans reveals connections to nitric oxide metabolism
Nitrate is a dominant form of inorganic nitrogen (N) in soils and can be efficiently assimilated by bacteria, fungi and plants. We studied here the transcriptome of the short‐term nitrate responseExpand
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The function of CreA, the carbon catabolite repressor of Aspergillus nidulans, is regulated at the transcriptional and post‐transcriptional level
The creA gene of A. nidulans encodes a wide‐domain regulatory protein mediating carbon catabolite repression. Northern blot analysis of creA mRNA revealed a complex expression profile: the additionExpand
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N-Glycan Modification in Aspergillus Species
ABSTRACT The production by filamentous fungi of therapeutic glycoproteins intended for use in mammals is held back by the inherent difference in protein N-glycosylation and by the inability of theExpand
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Heterochromatin influences the secondary metabolite profile in the plant pathogen Fusarium graminearum
Highlights ► Heterochromatin protein characterized in F. graminearum. ► Heterochromatic marks regulate secondary metabolism in this fungus. ► Aurofusarin and DON production under Hep1 regulation. ►Expand
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