• Publications
  • Influence
Immunotherapy: what lies beyond.
Allergen immunotherapy has been used to treat allergic diseases, such as asthma, allergic rhinitis, and venom allergy, since first described over a century ago. The current standard of care in theExpand
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Future forms of immunotherapy.
Allergic respiratory diseases affect approximately 15% of the US population. Allergen immunotherapy has been a treatment option for diseases such as allergic rhinitis, allergic asthma, and venomExpand
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Cannabis (hemp) positive skin tests and respiratory symptoms.
BACKGROUND We have noted several patients who had rhinitis and/or asthma symptoms when exposed to Cannabis plants in the summer months. Cannabis plants are common in the Midwest. OBJECTIVES ToExpand
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Anti-IgE Treatment for Disorders Other Than Asthma
  • J. Stokes
  • Medicine
  • Front. Med.
  • 21 September 2017
Immunoglobulin E (IgE) plays a key role in the pathogenesis of many allergic diseases. Thus, IgE-mediated immunologic pathways are an attractive target for intervention in allergic diseases.Expand
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Characterization of asthma endotypes: implications for therapy.
  • J. Stokes, T. Casale
  • Medicine
  • Annals of allergy, asthma & immunology : official…
  • 1 August 2016
OBJECTIVE To describe the concept of precision medicine in treating severe asthma and the utility of relevant biomarkers. DATA SOURCES PubMed was searched for published articles on human clinicalExpand
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The use of anti-IgE therapy beyond allergic asthma.
Omalizumab is a monoclonal anti-IgE antibody that has been used to treat allergic asthma for over a decade. The use of omalizumab to treat other diseases has largely been limited to case reportsExpand
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The effects of an H3 receptor antagonist (PF-03654746) with fexofenadine on reducing allergic rhinitis symptoms.
BACKGROUND Nasal H(3) receptors might have a role in mediating the effects of histamine in patients with allergic rhinitis. OBJECTIVE This study explored the effect of the potent oral H(3) receptorExpand
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Rationale for new treatments aimed at IgE immunomodulation.
  • J. Stokes, T. Casale
  • Medicine
  • Annals of allergy, asthma & immunology : official…
  • 1 September 2004
OBJECTIVE To review potential or current therapies that decrease IgE synthesis or effects. DATA SOURCES Relevant literature in peer-reviewed journals and abstracts from national meetings. STUDYExpand
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Time-dependent effects of inhaled corticosteroids on lung function, bronchial hyperresponsiveness, and airway inflammation in asthma.
BACKGROUND Exhaled nitric oxide (F(ENO)) and exhaled breath condensate (EBC) are noninvasive markers that directly measure airway inflammation and may potentially be useful in assessing asthmaExpand
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Promising future therapies for asthma.
  • J. Stokes
  • Medicine
  • International immunopharmacology
  • 1 November 2014
Asthma affects 300 million people worldwide and that number has been increasing especially in developed countries. The current standard of care for asthma treatment is based on 2 key pathologicalExpand
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