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Bacterial rhodopsin: evidence for a new type of phototrophy in the sea.
TLDR
The results demonstrate that archaeal-like rhodopsins are broadly distributed among different taxa, including members of the domain Bacteria, and indicate that a previously unsuspected mode of bacterially mediated light-driven energy generation may commonly occur in oceanic surface waters worldwide. Expand
Genome sequence of Halobacterium species NRC-1.
TLDR
Analysis of the genome sequence shows the presence of pathways for uptake and utilization of amino acids, active sodium-proton antiporter and potassium uptake systems, sophisticated photosensory and signal transduction pathways, and DNA replication, transcription, and translation systems resembling more complex eukaryotic organisms. Expand
Natural light-gated anion channels: A family of microbial rhodopsins for advanced optogenetics
TLDR
Anion channel rhodopsins (ACRs), a family of light-gated anion channels from cryptophyte algae that provide highly sensitive and efficient membrane hyperpolarization and neuronal silencing through light- gated chloride conduction, are described. Expand
Proteorhodopsin phototrophy in the ocean
TLDR
It is reported that photoactive proteorhodopsin is present in oceanic surface waters and evidence is provided of an extensive family of globally distributed proteorodopsin variants that seem to be spectrally tuned to different habitats—absorbing light at different wavelengths in accordance with light available in the environment. Expand
Two rhodopsins mediate phototaxis to low- and high-intensity light in Chlamydomonas reinhardtii
TLDR
It is demonstrated that two rhodopsins, identified from cDNA sequences, function as low- and high-light-intensity phototaxis receptors in the eukaryotic alga Chlamydomonas reinhardtii by in vivo analysis of photoreceptor electrical currents and motility responses in transformants with RNA interference directed against each of the r Rhodopsin genes. Expand
Retinylidene proteins: structures and functions from archaea to humans.
TLDR
The aims of this review are to examine this group of photoactive proteins as a whole, to summarize the current understanding of structure/function relationships in the best-studied examples, and to report recent new developments. Expand
Molecular mechanism of photosignaling by archaeal sensory rhodopsins.
TLDR
The SR-Htr signaling complexes allow studies of the biophysical chemistry of signal generation and relay, from the photobiophysics of initial excitation of the receptors to the final output at the level of the flagellar motor switch, revealing fundamental principles of sensory transduction. Expand
Non-genetic individuality: chance in the single cell
TLDR
Poissonian fluctuation of small numbers of generator molecules can explain the individuality of bacterial cells grown in homogeneous conditions and may apply to such processes as differentiation and asynchrony of cultures. Expand
Diversification and spectral tuning in marine proteorhodopsins
TLDR
It is demonstrated that a single amino acid residue at position 105 that functions as a spectral tuning switch and accounts for most of the spectral difference between the two pigment families is the major determinant of proteorhodopsin wavelength regulation in natural marine environments. Expand
New Insights into Metabolic Properties of Marine Bacteria Encoding Proteorhodopsins
TLDR
It is shown that some proteorhodopsin-containing bacteria possess a retinal biosynthetic pathway and a reverse sulfite reductase operon, employed by prokaryotes oxidizing sulfur compounds, Thus, these novel phototrophs are an unexpectedly large and metabolically diverse component of the marine microbial surface water. Expand
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