• Publications
  • Influence
Multitarget stool DNA testing for colorectal-cancer screening.
  • J. Souverijn
  • Medicine
  • The New England journal of medicine
  • 10 July 2014
Effect of simvastatin on renal function in autosomal dominant polycystic kidney disease.
It is concluded that simvastatin treatment can ameliorate renal function in ADPKD patients, by increasing renal plasma flow, possibly via improvement of endothelial function. Expand
Long-term treatment of intestinal helminths increases mite skin-test reactivity in Gabonese schoolchildren.
Anthelminthic treatment of chronically infected children results in increased atopic reactivity, which indicates that helminths directly suppress allergic reactions. Expand
Serum Albumin, Coronary Heart Disease Risk, and Mortality in an Elderly Cohort
We investigated associations of serum albumin with the incidence and mortality of coronary heart disease among men from the Zutphen Elderly Study. In 1985, 820 men were randomly selected from aExpand
Assessment of myocardial damage in patients with acute myocardial infarction by serial measurement of serum alpha-hydroxybutyrate dehydrogenase levels.
Analysis of data shows that the larger HBDH-infarct sizes were found to be associated significantly with signs of heart failure, low stroke index and low ejection fraction, and presence of tachycardias and interventricular conduction disturbances, and death in the first year after infarction. Expand
The effect of age on serum concentrations of albumin and alpha 1-acid glycoprotein.
Data show that in healthy subjects the HSA concentration decreases with increasing age, whereas age, uncomplicated by disease does not influence AAG concentration. Expand
Combining salicylate and enalapril in patients with coronary artery disease and heart failure.
The risk is low that salicylate will substantially reduce the benefit of enalapril in patients with heart failure by de-unloading the ventricle, according to the results of a double blind, crossover study. Expand
Clinical significance of a low serum alkaline phosphatase.
The reasons for a low serum alkaline phosphatase activity were reviewed in a 1-yr retrospective study of all the results emanating from a central, university hospital laboratory, and hypophosphatasaemia was encountered in neonates undergoing exchange transfusions with plasma, in patients receiving chemotherapy and during cardio-pulmonary bypass. Expand
Long‐term use of proton pump inhibitors and vitamin B12 status in elderly individuals
This work has shown that short‐term use of proton pump inhibitors decreases the absorption of vitamin B12, but the results of studies into long‐term proton pumps inhibitor use and vitamin B 12 deficiency are inconsistent. Expand
Atrial natriuretic peptide improves pulmonary gas exchange in subjects exposed to hypoxia.
The effect of low-dose ANP was studied in 11 healthy mountaineers exposed to hypoxia in a single-blind, placebo-controlled, cross-over design and indicated that approximately 10% of the plasma volume had permeated into the interstitium. Expand