J. Smythies

Publications51
h-index16
Citations850
Highly Influential Citations33
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The claustrum : structural, functional, and clinical neuroscience
TLDR
The Claustrum develops a unifying hypothesis about the claustrum's role in consciousness, as well as the integration of sensory information and other higher brain functions, and discusses the involvement of the claUSTrum with autism, schizophrenia, epilepsy, Alzheimer's disease, and Parkinson's disease.
Hypotheses relating to the function of the claustrum
TLDR
It is proposed that the claustrum functions as a detector and integrator of synchrony in the axonal trains in its afferent inputs and may play a strong role in the control of interactive processes in different parts of the brain, and in theControl of voluntary behavior.
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The Functional Neuroanatomy of Awareness: With a Focus on the Role of Various Anatomical Systems in the Control of Intermodal Attention
  • J. Smythies
  • Biology, Psychology
    Consciousness and Cognition
  • 1 December 1997
TLDR
The conclusion is reached that the brain may work by largely nonlinear parallel processing and much intramodal shifts of attention may be effected by intracortical, or multiple corticothalamic mechanisms (small local "flashlights" rather than one major "searchlight").
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Death and Personal Survival: The Evidence for Life after Death . By R. Almeder. (Pp. 285; $17.95.) Rowman and Littlefield : Lanham, Maryland. 1992.
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An empirical refutation of the direct realist theory of perception
There are currently two main philosophical theories of perception ‐ Direct Realism and the Representative Theory. The former is supported by most contemporary philosophers, whereas the latter forms…
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The role of telocytes in morphogenetic bioelectrical signaling: once more unto the breach
TLDR
This paper explores the possibility that telocytes play a major role in morphogenetic bioelectrical signaling and investigates the role of EMT in this signaling cascade.
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Telocytes, exosomes, gap junctions and the cytoskeleton: the makings of a primitive nervous system?
TLDR
Telocytes form a dense convoluted network linking TCs with each other, and with many other cell types including secretory acini and exocrine epithelial ducts, nerve fibers, macrophages, and blood vessels, which suggests that TCs are involved in integrating neural, vascular and endocrine processes.
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The neurotoxicity of glutamate, dopamine, iron and reactive oxygen species: Functional interrelationships in health and disease: A review — discussion
TLDR
The purpose of this review is to examine the less well known complex ways in which their normal biological, as well as their neurotoxic activity, are interconnected in relation to fundamental neuronal functions.
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Redox aspects of signaling by catecholamines and their metabolites.
TLDR
Evidence is presented that abnormalities in this system may contribute to the pathogenesis of Parkinson's disease and schizophrenia.
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Hypotheses relating to the function of the claustrum II: does the claustrum use frequency codes?
TLDR
Arguments are reviewed that both subhypotheses 2 and 3 are, at present, unsatisfactory and the question that is addressed now is what is the validity of subhypothesis 1 and 2.
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