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Quercetin: Critical Evaluation as an Antileishmanial Agent In Vivo in Hamsters Using Different Vesicular Delivery Modes
- S. Sarkar, S. Mandal, J. Sinha, S. Mukhopadhyay, N. Das, M. Basu
- Biology, Medicine
- Journal of drug targeting
- 1 January 2002
Chemotherapy is still a major challenge for in vivo drug targeting to macrophages. Toxicity remains the major obstacle for the most potent drugs already known in the therapy of leishmaniasis. Thus,… Expand
Targeting of liposomal andrographolide to L. donovani-infected macrophages in vivo.
Despite the rapid development in medicinal and pharmaceutical technology, the targeting of drugs to phagocytic cells in macrophage-related diseases still remains a major unsolved problem. By using… Expand
Liposomal antioxidants in combating ischemia-reperfusion injury in rat brain.
Liposome-encapsulated antioxidants have been tested in vivo to prevent oxidative attack during cerebral ischemia and reperfusion. Oxidative stress is a causal factor in the neuropathogenesis of… Expand
Bacopasaponin C: Critical Evaluation of Anti-Leishmanial Properties in Various Delivery Modes
Bacopasaponin C, an indigenous glycoside, was isolated from Indian medicinal plant Bacopa monniera (b. brahmi) and was tested for antileishmanial properties both in free and in various delivery… Expand
Targeting of Liposomal Flavonoid to Liver in Combating Hepatocellular Oxidative Damage
- A. Mandal, J. Sinha, S. Mandal, S. Mukhopadhyay, N. Das
- Chemistry, Medicine
- Drug delivery
- 1 January 2002
The efficacy of mannosylated liposome formulations with Quercetin (QC, a flavonoid antioxidant isolated from indigenous origin) has been tested in vivo against carbon tetrachloride(CCl 4) -induced… Expand