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Comparison of Tripterygium wilfordii Hook F Versus Sulfasalazine in the Treatment of Rheumatoid Arthritis
- R. Goldbach-Mansky, M. Wilson, +14 authors Peter E. Lipsky
- Annals of Internal Medicine
- 18 August 2009
Context In Chinese medicine, extracts of Tripterygium wilfordii Hook F (TwHF, known as lei gong teng or thunder god vine) are used to treat autoimmune and inflammatory conditions. Small clinical… Expand
Safety and Efficacy of Tofacitinib, an Oral Janus Kinase Inhibitor, for the Treatment of Rheumatoid Arthritis in Open-label, Longterm Extension Studies
Objective. To describe the longterm safety and efficacy profile of tofacitinib in patients with moderate to severe active rheumatoid arthritis (RA). Methods. Data were pooled from 2 open-label… Expand
Safety and efficacy of tofacitinib for up to 9.5 years in the treatment of rheumatoid arthritis: final results of a global, open-label, long-term extension study
BackgroundFinal data are presented for the ORAL Sequel long-term extension (LTE) study evaluating the safety and efficacy of tofacitinib 5 mg and 10 mg twice daily (BID) for up to 9.5 years in… Expand
Tramadol/acetaminophen combination tablets for the treatment of osteoarthritis flare pain: a multicenter, outpatient, randomized, double-blind, placebo-controlled, parallel-group, add-on study.
BACKGROUND In a flare of osteoarthritis (OA) pain, increasing the dose of standard anti-inflammatory or routine analgesic drugs may not be practical because of an increased incidence of side effects.… Expand
The effect of tofacitinib on pneumococcal and influenza vaccine responses in rheumatoid arthritis
- K. Winthrop, J. Silverfield, +11 authors C. Bingham
- Annals of the rheumatic diseases
- 20 March 2015
Objective To evaluate tofacitinib's effect upon pneumococcal and influenza vaccine immunogenicity. Methods We conducted two studies in patients with rheumatoid arthritis using the 23-valent… Expand
Tenidap in rheumatoid arthritis. A 24-week double-blind comparison with hydroxychloroquine-plus-piroxicam, and piroxicam alone.
OBJECTIVE To compare the clinical efficacy, effect on serum C-reactive protein (CRP), serum amyloid A (SAA), and plasma interleukin-6 (IL-6) levels, and safety of tenidap with a combination of… Expand
Rheumatoid vasculitis: survival and associated risk factors.
- R. Vollertsen, D. Conn, D. Ballard, D. Ilstrup, R. E. Kazmar, J. Silverfield
- 1 November 1986
We describe the clinical and laboratory characteristics of 52 patients with rheumatoid vasculitis whose condition was diagnosed at a tertiary care center between 1974 and 1981, and we report their… Expand
T‐Lymphocyte Subsets During Pregnancy and the Menstrual Cycle
- C. Coulam, J. Silverfield, R. E. Kazmar, C. G. Fathman
- American journal of reproductive immunology…
- 1 September 1983
ABSTRACT: Many observations suggest that cellular immunity is depressed during gestation. To define alterations in subsets of circulating lymphocytes during pregnancy, we compared the percentages of… Expand
Tramadol/Acetaminophen Combination Tablets for the Treatment of Pain Associated with Osteoarthritis Flare in an Elderly Patient Population
- N. Rosenthal, J. Silverfield, Shu-chen Wu, Donna Jordan, M. Kamin
- Journal of the American Geriatrics Society
- 1 March 2004
Objectives: To evaluate the efficacy and safety of adding tramadol 37.5 mg/acetaminophen (APAP) 325 mg combination tablets (tramadol/APAP) to existing therapy for painful osteoarthritis (OA) flare in… Expand
Dose response and safety study of meloxicam up to 22.5 mg daily in rheumatoid arthritis: a 12 week multicenter, double blind, dose response study versus placebo and diclofenac.
OBJECTIVE This Phase III, placebo and active controlled, multicenter trial evaluated the efficacy and safety of meloxicam 7.5, 15, and 22.5 mg daily for the treatment of rheumatoid arthritis (RA). … Expand