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Expression of pro-inflammatory cytokines in rainbow trout (Oncorhynchus mykiss) during an infection with Ichthyophthirius multifiliis.
The parasitic ciliate Ichthyophthirius multifiliis induces expression of immune relevant genes in rainbow trout, Oncorhynchus mykiss (Walbaum).
Data suggest that complement is involved in immune reactions against I. multifiliis and that mucosal antibodies might be produced at the site of infection, as well as in the lymphoid organs.
Host responses against the fish parasitizing ciliate Ichthyophthirius multifiliis.
Comparison of immobilization assays and enzyme‐linked immunosorbent assays for detection of rainbow trout antibody‐titres against Ichthyophthirius multifiliis Fouquet, 1876
Skin expression of IL-1beta in East Atlantic salmon, Salmo salar L., highly susceptible to Gyrodactylus salaris infection is enhanced compared to a low susceptibility Baltic stock.
Streptococcus pneumoniae: proteomics of surface proteins for vaccine development.
- C. Morsczeck, T. Prokhorova, P. Schrotz-King
- Biology, MedicineClinical microbiology and infection : the…
Two candidate proteins, the putative lipoate protein ligase (Lpl) and the ClpP protease, resulted in a reduced CFU titre and a trend towards reduced mortality in an animal sepsis model for investigating new S. pneumoniae protein vaccines.
Concizumab, an anti‐tissue factor pathway inhibitor antibody, induces increased thrombin generation in plasma from haemophilia patients and healthy subjects measured by the thrombin generation assay
- E. K. Waters, J. Sigh, U. Friedrich, I. Hilden, B. Sørensen
- Biology, MedicineHaemophilia : the official journal of the World…
- 1 September 2017
It is investigated how concizumab affects thrombin generation following ex vivo spiking in plasma from haemophilia patients using the TGA, and if the assay can detect the effect of multiple s.c. concIZumab doses in healthy subjects.
Production of acylated homoserine lactones by different serotypes of Vibrio anguillarum both in culture and during infection of rainbow trout.
The data show that AHLs are produced by almost all V. anguillarum strains and that no clear pattern relating AHL production to disease or virulence appear.
Amoebic gill infections of rainbow trout in freshwater ponds
It was found that extensive hyperplasia of gill filaments, clubbing and fusion of filaments and lamellae occurred at high frequency and the amoebae could not be ascribed to the known freshwater amoEBa genera recorded in rainbow trout.
Partial cross protection against Ichthyophthirius multifiliis in Gyrodactylus derjavini immunized rainbow trout
Fish partly immune to the ectoparasitic monogenean G. derjavini became less infected and experienced lower mortality than naive fish when exposed to I. multifiliis infection, suggesting that non-specific factors including complement could be partly responsible for the host response against infections with this ciliate.