J. Shin

Publications114
h-index22
Citations1,619
Highly Influential Citations69
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Fucosterol isolated from Undaria pinnatifida inhibits lipopolysaccharide-induced production of nitric oxide and pro-inflammatory cytokines via the inactivation of nuclear factor-κB and p38…
It has been reported that fucosterol has anti-diabetic, anti-oxidant, and anti-osteoporotic effects. We investigated the anti-inflammatory effects and the underlying molecular mechanism of fucosterol… Expand
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Anti-inflammatory effects of methanol extract of Patrinia scabiosaefolia in mice with ulcerative colitis.
ETHNOPHARMACOLOGICAL RELEVANCE Patrinia scabiosaefolia Fisch is used in folk medicines to treat intestinal abscesses, acute appendicitis, and dysentery in Asia. Although recent reports indicate that… Expand
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Sulfuretin isolated from heartwood of Rhus verniciflua inhibits LPS-induced inducible nitric oxide synthase, cyclooxygenase-2, and pro-inflammatory cytokines expression via the down-regulation of…
It has been reported that Rhusverniciflua exhibits anti-inflammatory, anti-oxidant and anti-cancer activities. However, little is known about biological activity of sulfuretin, a flavonoid isolated… Expand
  • 67
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Chloroform fraction of Solanum tuberosum L. cv Jayoung epidermis suppresses LPS-induced inflammatory responses in macrophages and DSS-induced colitis in mice.
  • S. Lee, J. Shin, +8 authors K. Lee
  • Chemistry, Medicine
  • Food and chemical toxicology : an international…
  • 2014
In this study, the authors investigated the molecular mechanism underlying the antiinflammatory effects of the chloroform fraction of the peel of 'Jayoung' (CFPJ), a color-fleshed potato, on… Expand
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Anti-inflammatory effects of madecassic acid via the suppression of NF-kappaB pathway in LPS-induced RAW 264.7 macrophage cells.
We have investigated the anti-inflammatory effects of madecassic acid and madecassoside isolated from Centella asiatica (Umbelliferae) on lipopolysaccharide (LPS)-stimulated RAW 264.7 murine… Expand
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Fraxinellone inhibits lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 expression by negatively regulating nuclear factor-kappa B in RAW 264.7 macrophages cells.
Fraxinellone is formed by the natural degradation of limonoids isolated from the root bark of Dictamnus dasycarpus. Fraxinellone has been reported to possess neuroprotective and vasorelaxing… Expand
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  • PDF
Xanthotoxin suppresses LPS‐induced expression of iNOS, COX‐2, TNF‐&agr;, and IL‐6 via AP‐1, NF‐&kgr;B, and JAK‐STAT inactivation in RAW 264.7 macrophages
&NA; Although xanthotoxin has been reported to possess skin‐protective and anti‐oxidative properties, its anti‐inflammatory capacity has not been studied to date. Therefore, we investigated this role… Expand
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Quaternary alkaloid, pseudocoptisine isolated from tubers of Corydalis turtschaninovi inhibits LPS-induced nitric oxide, PGE(2), and pro-inflammatory cytokines production via the down-regulation of…
It is well known that pro-inflammatory mediators like nitric oxide (NO), prostaglandin E(2) (PGE(2)), tumor necrosis factor-alpha (TNF-alpha), and interleukin-6 (IL-6) contribute to the courses of… Expand
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Ethanol Extract of Potentilla supina Linne Suppresses LPS‐induced Inflammatory Responses through NF‐κB and AP‐1 Inactivation in Macrophages and in Endotoxic mice
In this study, we investigated the antiinflammatory effects of ethanol extracts of Potentilla. supina Linne (EPS) in lipopolysaccharide (LPS)‐induced RAW 264.7 macrophages and septic mice. EPS… Expand
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Anti-inflammatory effect of anemarsaponin B isolated from the rhizomes of Anemarrhena asphodeloides in LPS-induced RAW 264.7 macrophages is mediated by negative regulation of the nuclear…
Anemarrhena asphodeloides is widely used in traditional Chinese medicine, and is known to have anti-diabetic and diuretic effects. In this study, we evaluated the anti-inflammatory effects of… Expand
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