• Publications
  • Influence
MicroRNA-382 induced by HIF-1α is an angiogenic miR targeting the tumor suppressor phosphatase and tensin homolog
TLDR
Results suggest that miR-382 induced by hypoxia promotes angiogenesis and acts as an angiogenic oncogene by repressing PTEN.
A study of the human skin-whitening effects of resveratryl triacetate
TLDR
RTA incorporated into cosmetic formulations can whiten human skin without inducing skin irritation, and the skin-whitening efficacy of a cosmetic formulation containing 0.4 % RTA was evaluated in two different test models.
Ecklonia cava Extract and Dieckol Attenuate Cellular Lipid Peroxidation in Keratinocytes Exposed to PM10
TLDR
It is suggested that the polyphenolic constituents of E. cava, such as dieckol, attenuated the oxidative and inflammatory reactions in skin cells exposed to airborne particulate matter.
Skin Barrier Abnormalities and Immune Dysfunction in Atopic Dermatitis
TLDR
Recent findings on AD and the possible underlying mechanisms involved in its pathogenesis are explored, which is characterized by dysregulation of immunological and skin barrier integrity and function, supporting the idea that AD is a systemic disease.
Human skin‐depigmenting effects of resveratryl triglycolate, a hybrid compound of resveratrol and glycolic acid
  • D. Jo, J. Seok, Y. Boo
  • Biology
    International journal of cosmetic science
  • 1 June 2018
TLDR
This study aimed to examine the in vivo skin‐depigmenting efficacy of RTG in human participants to inhibit cellular melanin synthesis in vitro and to demonstrate its applicability in vivo.
p-Coumaric Acid Attenuates UVB-Induced Release of Stratifin from Keratinocytes and Indirectly Regulates Matrix Metalloproteinase 1 Release from Fibroblasts
  • J. Seok, Y. Boo
  • Biology
    The Korean journal of physiology & pharmacology…
  • 30 April 2015
TLDR
It is demonstrated that the use of UV absorbers such as p-CA would reduce UV-induced SFN-centered signaling events involved in skin photoaging.
Ascorbyl coumarates as multifunctional cosmeceutical agents that inhibit melanogenesis and enhance collagen synthesis
TLDR
It is suggested that A-3-p-C and A-2- p-C could be used as multifunctional cosmeceutical agents for the attenuation of certain aspects of skin aging.
Anti-Inflammatory Effects of Pomegranate Peel Extract in THP-1 Cells Exposed to Particulate Matter PM10
TLDR
PPE constituents, punicalagin and ellagic acid, attenuated PM10-induced monocyte adhesion to endothelial cells, and punicalsagin was less cytotoxic compared to ellagic Acid.
Therapeutic regulation of the NLRP3 inflammasome in chronic inflammatory diseases.
TLDR
Recent efforts to develop therapeutic applications targeting the NLRP3 inflammasome to cure and prevent chronic inflammatory diseases are summarized and small molecule inhibitors are classified depending on direct or indirect targeting mechanism to describe the current status of the development of pharmacological inhibitors.
Anti-melanogenic effects of resveratryl triglycolate, a novel hybrid compound derived by esterification of resveratrol with glycolic acid
  • S. Park, J. Seok, Y. Boo
  • Biology, Chemistry
    Archives of Dermatological Research
  • 8 April 2016
TLDR
RTG can attenuate cellular melanin synthesis effectively through the suppression of MITF-dependent expression of melanogenic enzymes and the inhibition of catalytic activity of TYR enzyme, suggesting potential for use as a cosmeceutical ingredient for skin whitening.
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