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- Publications
- Influence
An investigation of the mobility separation of some peptide and protein ions using a new hybrid quadrupole/travelling wave IMS/oa-ToF instrument
- S. Pringle, K. Giles, +6 authors J. Scrivens
- Chemistry
- 1 March 2007
Ion mobility coupled with mass spectrometry has evolved into a powerful analytical technique for investigating the gas-phase structures of biomolecules. Here we present the mobility separation of… Expand
Bacterial flavin-containing monooxygenase is trimethylamine monooxygenase
- Y. Chen, Nisha A. Patel, Andrew Crombie, J. Scrivens, J. Murrell
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 17 October 2011
Flavin-containing monooxygenases (FMOs) are one of the most important monooxygenase systems in Eukaryotes and have many important physiological functions. FMOs have also been found in bacteria;… Expand
A comparison of labeling and label-free mass spectrometry-based proteomics approaches.
- V. J. Patel, K. Thalassinos, +4 authors J. Scrivens
- Biology, Medicine
- Journal of proteome research
- 8 June 2009
The proteome of the recently discovered bacterium Methylocella silvestris has been characterized using three profiling and comparative proteomics approaches. The organism has been grown on two… Expand
Travelling wave ion mobility mass spectrometry studies of protein structure: biological significance and comparison with X-ray crystallography and nuclear magnetic resonance spectroscopy measurements.
- C. A. Scarff, K. Thalassinos, Gillian R. Hilton, J. Scrivens
- Chemistry, Medicine
- Rapid communications in mass spectrometry : RCM
- 30 October 2008
The three-dimensional conformation of a protein is central to its biological function. The characterisation of aspects of three-dimensional protein structure by mass spectrometry is an area of much… Expand
The use of recently described ionisation techniques for the rapid analysis of some common drugs and samples of biological origin.
- J. Williams, V. J. Patel, R. Holland, J. Scrivens
- Chemistry, Medicine
- Rapid communications in mass spectrometry : RCM
- 15 May 2006
Three ionisation techniques that require no sample preparation or extraction prior to mass analysis have been used for the rapid analysis of pharmaceutical tablets and ointments. These methods were… Expand
Coupling desorption electrospray ionisation and neutral desorption/extractive electrospray ionisation with a travelling-wave based ion mobility mass spectrometer for the analysis of drugs.
- J. Williams, J. Scrivens
- Chemistry, Medicine
- Rapid communications in mass spectrometry : RCM
- 30 January 2008
Desorption electrospray ionisation (DESI) and neutral desorption/extractive electrospray ionisation (EESI) have been coupled to a hybrid quadrupole travelling-wave (T-Wave)-based ion mobility… Expand
Estimating collision cross sections of negatively charged N-glycans using traveling wave ion mobility-mass spectrometry.
- J. Hofmann, W. Struwe, C. A. Scarff, J. Scrivens, D. Harvey, K. Pagel
- Chemistry, Medicine
- Analytical chemistry
- 13 October 2014
Glycosylation is one of the most common post-translational modifications occurring in proteins. A detailed structural characterization of the involved carbohydrates, however, is still one of the… Expand
Probing hemoglobin structure by means of traveling-wave ion mobility mass spectrometry
- C. A. Scarff, V. J. Patel, K. Thalassinos, J. Scrivens
- Chemistry, Medicine
- Journal of the American Society for Mass…
- 1 April 2009
Hemoglobin (Hb) is a tetrameric noncovalent complex consisting of two α- and two β-globin chains each associated with a heme group. Its exact assembly pathway is a matter of debate. Disorders of… Expand
Urbilaterian origin of paralogous GnRH and corazonin neuropeptide signalling pathways
- Shi Tian, M. Zandawala, +4 authors M. Elphick
- Medicine
- Scientific reports
- 28 June 2016
Gonadotropin-releasing hormone (GnRH) is a key regulator of reproductive maturation in humans and other vertebrates. Homologs of GnRH and its cognate receptor have been identified in… Expand
Characterization of phosphorylated peptides using traveling wave-based and drift cell ion mobility mass spectrometry.
- K. Thalassinos, M. Grabenauer, Susan E Slade, Gillian R. Hilton, M. Bowers, J. Scrivens
- Chemistry, Medicine
- Analytical chemistry
- 2009
Phosphorylation is one the most studied and important post translational modifications. Nano electrospray mass spectrometry coupled with traveling wave (T-Wave)-based ion mobility has been used to… Expand