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FISH-based determination of HER2 status in circulating tumor cells isolated with the microfluidic CEE™ platform.
Determination of HER2 status in breast cancer patients is considered standard practice for therapy selection. However, tumor biopsy in patients with recurrent and/or metastatic disease is not always… Expand
Applying the TOC thinking process in manufacturing: A case study
A case study is presented to illustrate the application of the Theory of Constraints thinking process logic tools in a manufacturing environment. The study firm performs design activities related to… Expand
Reference Size Matching, Whole-Genome Amplification, and Fluorescent Labeling as a Method for Chromosomal Microarray Analysis of Clinically Actionable Copy Number Alterations in Formalin-Fixed,…
- Shelly R. Gunn, Shailin Govender, +5 authors Philip D. Cotter
- Medicine, Biology
- The Journal of molecular diagnostics : JMD
- 1 May 2018
Cancer genome copy number alterations (CNAs) assist clinicians in selecting targeted therapeutics. Solid tumor CNAs are most commonly evaluated in formalin-fixed, paraffin-embedded (FFPE) tissue by… Expand
Abstract 5172: Fluorescence labeling of cytokeratin-negative circulating tumor cells in peripheral blood: A new paradigm for the study of cancer progression
Introduction: The measurement of circulating tumor cells (CTCs) in blood generally requires either anti-EpCAM for capture, anti-cytokeratin (CK) for detection, or both. However, EpCAM and CK are… Expand
P1-07-13: Efficiency of a Laboratory Developed HER2 FISH Test on Circulating Tumor Cells.