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Children and adolescents with velocardiofacial syndrome: a volumetric MRI study.
TLDR
Aberrant brain morphology is associated with velocardiofacial syndrome and these changes are potentially related to the language and learning deficits associated with the syndrome and may provide clues about neurodevelopmental pathways associated with schizophrenia.
Neuroanatomy of Down's syndrome: a high-resolution MRI study.
TLDR
The presence of these abnormalities from an early age suggests that fetal or early postnatal developmental differences may underlie the observed pattern of neuroanatomic abnormalities and contribute to the specific cognitive and developmental deficits seen in individuals with Down's syndrome.
Differences in genetic and environmental influences on the human cerebral cortex associated with development during childhood and adolescence
TLDR
The observation that regions associated with complex cognitive processes such as language, tool use, and executive function are more heritable in adolescents than children is consistent with previous studies showing that IQ becomes increasingly heritable with maturity.
Amygdala and hippocampal volumes in children with Down syndrome: A high-resolution MRI study
TLDR
Findings suggest that the hippocampal volume reduction seen in adults with Down syndrome may be primarily due to early developmental differences rather than neurodegenerative changes.
Genetic and environmental influences on the size of specific brain regions in midlife: The VETSA MRI study
TLDR
The results did not indicate lateralized heritability differences or greater genetic influences on the size of regions underlying higher cognitive functions, which provides key information for imaging genetic studies and other studies of brain phenotypes and endophenotypes.
Identification of genetically mediated cortical networks: a multivariate study of pediatric twins and siblings.
TLDR
Findings are largely concordant with other multivariate studies of brain structure and function, the twin literature, and current understanding on the role of genes in cortical neurodevelopment.
Pilot multimodal twin imaging study of generalized anxiety disorder
TLDR
Generalized anxiety disorder is a common chronic condition that is relatively understudied compared to other psychiatric syndromes; however, no genetically informative research has examined the potential sources of reported brain differences.
Analysis of cerebral shape in Williams syndrome.
TLDR
Subjects with WMS have significantly different cerebral shape from normal controls, perhaps due to decreased parieto-occipital lobe volumes relative to frontal regions and similar observation in the corpus callosum may be associated with a decreased size of the splenium in WMS.
Neural Correlates of Auditory Perception in Williams Syndrome: An fMRI Study
TLDR
Functional magnetic resonance imaging is used to examine the neural basis of auditory processing of music and noise in Williams syndrome patients and age-matched controls and finds strikingly different patterns of neural organization between the groups.
A quantitative MRI study of posterior fossa development in velocardiofacial syndrome
TLDR
Structural alterations of the posterior fossa in VCFS are specifically limited to cerebellar vermis lobules VI--VII and pons, which could partially explain the neurobehavioral profile associated with VCFS.
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