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Activity sharpens the map during the regeneration of the retinotectal projection in goldfish
TLDR
Blocks during various portions of the regeneration process showed that lack of activity during the process of axonal elongation does not cause enlargement of the multiunit receptive fields, but lack ofActivity during the period of synapse formation and maturation does. Expand
Expansion of the half retinal projection to the tectum in goldfish: An electrophysiological and Anatomical study
TLDR
The topographical retino‐tectal projection of goldfish was electrophysiologically mapped at various intervals after surgical removal of the nasal half of the retina and pigment epithelium and it was demonstrated that retinal fiber terminals had invaded the caudal tectum. Expand
The Laminar organization of optic nerve fibres in the tectum of goldfish
  • J. Schmidt
  • Chemistry, Medicine
  • Proceedings of the Royal Society of London…
  • 1 August 1979
TLDR
The cobalt procedure was used to visualize the profiles of the optic fibres in the various tectal laminae, and it was found that the fastest conducting retinotectal fibres make their synapses most superficially, the opposite of the arrangement in the frog tectum. Expand
MK801 increases retinotectal arbor size in developing zebrafish without affecting kinetics of branch elimination and addition.
Visual activity refines the retinotopic map formed on tectum during regeneration and development in goldfish through an N-methyl-D-aspartate (NMDA) receptor-mediated mechanism. Retinal arbors areExpand
Myosin light chain phosphorylation and growth cone motility.
According to the treadmill hypothesis, the rate of growth cone advance depends upon the difference between the rates of protrusion (powered by actin polymerization at the leading edge) and retrogradeExpand
Retinal fibers alter tectal positional markers during the expansion of the half retinal projection in goldfish
  • J. Schmidt
  • Biology, Medicine
  • The Journal of comparative neurology
  • 15 January 1978
TLDR
Half retinal fish were tested for changed markers following expansion and apparently tectal markers are induced by the retinal fibers, changed during expansion, and disappear during long‐term denervation. Expand
Kinase requirement for retinal growth cone motility.
TLDR
The MLCK inhibitors' effects both on growth cone morphology and on F-actin filaments (rhodamine-phalloidin staining) were similar to those caused by cytochalasin D, and are discussed in light of findings that inhibiting M LCK disrupts actin filament in astrocytes and fibroblasts. Expand
Activity-driven sharpening of the retinotectal projection in goldfish: development under stroboscopic illumination prevents sharpening.
TLDR
This study tested whether activity-driven refinement also occurs during development of the projection in larval and young adult goldfish, and whether it is blocked or synchronizing during regeneration of the retinotectal projection. Expand
Nucleus isthmi in goldfish: in vitro recordings and fiber connections revealed by HRP injections.
TLDR
The fist demonstration of a tectoisthmic projection in a cyprinid fish is demonstrated using recordings from nucleus isthmi and fine axons, which have not been reported in percomorph fishes, were shown to arise from tectal bipolar (type VI) neurons. Expand
Long-term potentiation and activity-dependent retinotopic sharpening in the regenerating retinotectal projection of goldfish: common sensitive period and sensitivity to NMDA blockers
  • J. Schmidt
  • Chemistry, Medicine
  • The Journal of neuroscience : the official…
  • 1 January 1990
TLDR
The results support the involvement of NMDA receptors in sharpening and suggest that the initial step in stabilizing appropriate branches may be a long- lasting increase in synaptic gain. Expand
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