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2015 ESC Guidelines for the diagnosis and management of pericardial diseases
ADA : adenosine deaminase AMI : acute myocardial infarction ANA : anti-nuclear antibody bFGF : basic fibroblast growth factor CK : creatine kinase CMR : cardiac magnetic resonance CMV :Expand
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Consensus document on the overlap phenotype COPD-asthma in COPD.
INTRODUCTION Although asthma and COPD are different pathologies, many patients share characteristics from both entities. These cases can have different evolutions and responses to treatment.Expand
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Molecular Analysis of the Contribution of the Capsular Polysaccharide and the Lipopolysaccharide O Side Chain to the Virulence of Klebsiella pneumoniae in a Murine Model of Pneumonia
ABSTRACT Klebsiella pneumoniae is a common cause of gram-negative bacterial nosocomial pneumonia. Two surface polysaccharides, lipopolysaccharide (LPS) O side chain and capsular polysaccharide (CPS),Expand
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Systemic effects of chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD) is characterised by an inappropriate/excessive inflammatory response of the lungs to respiratory pollutants, mainly tobacco smoking. Recently, besides theExpand
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Oxidative stress and airway inflammation in severe exacerbations of COPD
Background: A study was undertaken to assess both oxidative stress and inflammation in the lungs of patients with chronic obstructive pulmonary disease (COPD) during severe and very severeExpand
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Hypermutation Is a Key Factor in Development of Multiple-Antimicrobial Resistance in Pseudomonas aeruginosa Strains Causing Chronic Lung Infections
ABSTRACT Pseudomonas aeruginosa is the most relevant pathogen producing chronic lung infections in patients with chronic underlying diseases such as cystic fibrosis (CF), bronchiectasis, and chronicExpand
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Identification and prospective validation of clinically relevant chronic obstructive pulmonary disease (COPD) subtypes
Background Chronic obstructive pulmonary disease (COPD) is increasingly considered a heterogeneous condition. It was hypothesised that COPD, as currently defined, includes different clinicallyExpand
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Skeletal muscle apoptosis and weight loss in chronic obstructive pulmonary disease.
Patients with chronic obstructive pulmonary disease (COPD) often lose weight during the course of their disease. We hypothesized that this may be due to skeletal muscle apoptosis. To investigate thisExpand
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Telomere shortening in smokers with and without COPD
Telomeres are complex DNA–protein structures located at the end of eukaryotic chromosomes. Telomere length shortens with age in all replicating somatic cells. It has been shown that tobacco smokingExpand
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Patients with obstructive sleep apnea exhibit genioglossus dysfunction that is normalized after treatment with continuous positive airway pressure.
Obstructive sleep apnea syndrome (OSAS) is characterized by repetitive episodes of pharyngeal closure during sleep. The pathogenesis of OSAS is unclear. We hypothesized that the genioglossus (GG),Expand
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