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Self-curing membranes of chitosan/PAA IPNs obtained by radical polymerization: preparation, characterization and interpolymer complexation.
TLDR
The gravimetric measurements and the elemental analysis after some exhaustive PAA extraction support the existence of some PAA grafting on the reactive amine group of the chitosan. Expand
New starch-based thermoplastic hydrogels for use as bone cements or drug-delivery carriers
TLDR
The results obtained in the mechanical tests are in the range of those reported for typical PMMA bone cements, showing that it is possible to develop partially degradable cements with an adequate mechanical behavior. Expand
Evaluation of drug delivery characteristics of microspheres of PMMA-PCL-cholesterol obtained by supercritical-CO2 impregnation and by dissolution-evaporation techniques.
TLDR
A comparison of drug release from particles obtained using both methods, the supercritical and the conventional, is presented and it is shown that cholesterol release is higher in the conventional method. Expand
Cytotoxicity of Cyanoacrylate-Based Tissue Adhesives and Short-Term Preclinical In Vivo Biocompatibility in Abdominal Hernia Repair
TLDR
The CAs promoted proper mesh fixation and have potential to replace traditional suturing techniques in hernia repair; the CAs exhibited good tissue integration and effective short-term biocompatibility, with the slightest seroma and macrophage response induced by OCA. Expand
Osteogenic effect of local, long versus short term BMP-2 delivery from a novel SPU-PLGA-βTCP concentric system in a critical size defect in rats.
TLDR
The biocompatibility and high capacity of adaptation to the defect convert the herein proposed, new SPU polymer into a potential material for applications in tissue engineering and regenerative medicine. Expand
Low-density polypropylene meshes coated with resorbable and biocompatible hydrophilic polymers as controlled release agents of antibiotics.
TLDR
Experiments in vivo, based on the implantation of coated meshes, demonstrate that the system controls the infection in the animal (rabbits) for at least 30days and can be applied to other medical devices and implants for the application of new-generation antibiotics in a controlled release and targeted applications. Expand
New aspects of the effect of size and size distribution on the setting parameters and mechanical properties of acrylic bone cements.
TLDR
The use of PMMA particles with average diameter of 50-60 microns, and a relatively wide size distribution, significantly changes the curing parameters of the cement formulations in comparison with the classical behaviour of the commercial systems of CMW and Rostal, without any noticeable loss in the mechanical properties. Expand
Mechanical and rheological improvement of a calcium phosphate cement by the addition of a polymeric drug.
TLDR
The strengthening of the structure was related to the reduction of porosity and the lower size of the precipitated crystals, as observed by scanning electron microscopy. Expand
Porous starch-based drug delivery systems processed by a microwave route
TLDR
A new simple processing route to produce starch-based porous materials was developed based on a microwave baking methodology, incorporating a non-steroid anti-inflammatory agent as model drug with expectations that the developed methodology might be used for other drugs and growth factors. Expand
Oxidized dextrins as alternative crosslinking agents for polysaccharides: application to hydrogels of agarose-chitosan.
TLDR
The aim of this work was the development of hydrogel networks based on agarose and chitosan using oxidized dextrins as low cytotoxicity crosslinking agents, paying special attention to the study of the influence of the polysaccharide composition and oxidation degree of the dextRins in the final characteristics of the network. Expand
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