Author pages are created from data sourced from our academic publisher partnerships and public sources.
- Publications
- Influence
Genomic analyses identify molecular subtypes of pancreatic cancer
- P. Bailey, D. Chang, +99 authors S. Grimmond
- Biology, Medicine
- Nature
- 3 March 2016
Integrated genomic analysis of 456 pancreatic ductal adenocarcinomas identified 32 recurrently mutated genes that aggregate into 10 pathways: KRAS, TGF-β, WNT, NOTCH, ROBO/SLIT signalling, G1/S… Expand
Whole genomes redefine the mutational landscape of pancreatic cancer
- Nicola Waddell, M. Pajic, +86 authors S. Grimmond
- Biology, Medicine
- Nature
- 26 February 2015
Pancreatic cancer remains one of the most lethal of malignancies and a major health burden. We performed whole-genome sequencing and copy number variation (CNV) analysis of 100 pancreatic ductal… Expand
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
- A. Biankin, Nicola Waddell, +123 authors S. Grimmond
- Biology, Medicine
- Nature
- 24 October 2012
Pancreatic cancer is a highly lethal malignancy with few effective therapies. We performed exome sequencing and copy number analysis to define genomic aberrations in a prospectively accrued clinical… Expand
Whole-genome landscape of pancreatic neuroendocrine tumours
- A. Scarpa, D. Chang, +100 authors S. Grimmond
- Biology, Medicine
- Nature
- 2 March 2017
The diagnosis of pancreatic neuroendocrine tumours (PanNETs) is increasing owing to more sensitive detection methods, and this increase is creating challenges for clinical management. We performed… Expand
Immunohistochemistry for SDHB Divides Gastrointestinal Stromal Tumors (GISTs) into 2 Distinct Types
- A. Gill, A. Chou, +17 authors R. Clifton-Bligh
- Medicine
- The American journal of surgical pathology
- 1 March 2010
The Carney triad (CT) is gastrointestinal stromal tumor (GIST), paraganglioma, and pulmonary chondroma. The GISTs of CT show different clinical, molecular, and morphologic features to usual adult… Expand
Pyogenic liver abscess: an audit of 10 years' experience.
AIM
To describe our own experience with pyogenic liver abscesses over the past 10 years and investigate the risk factors associated with failure of initial percutaneous therapy.
METHODS
A… Expand
Postprandial lipemia: the origin of an early peak studied by specific dietary fatty acid intake during sequential meals.
- B. Fielding, J. Callow, R. M. Owen, J. Samra, D. Matthews, K. Frayn
- Chemistry, Medicine
- The American journal of clinical nutrition
- 1996
Previous studies have noted the presence of an early postprandial peak in plasma triacylglycerol concentration, particularly when successive meals have been consumed. We tested the hypothesis that… Expand
Succinate dehydrogenase-deficient GISTs are characterized by IGF1R overexpression
Succinate dehydrogenase-deficient gastrointestinal stromal tumors (GISTs) demonstrate unique pathological and clinical features, including the absence of activating mutations of KIT and PDGFRA, and… Expand
Precision Medicine for Advanced Pancreas Cancer: The Individualized Molecular Pancreatic Cancer Therapy (IMPaCT) Trial
- L. Chantrill, A. Nagrial, +26 authors A. Biankin
- Medicine
- Clinical Cancer Research
- 20 April 2015
Purpose: Personalized medicine strategies using genomic profiling are particularly pertinent for pancreas cancer. The Individualized Molecular Pancreatic Cancer Therapy (IMPaCT) trial was initially… Expand
Peripancreatic pseudoaneurysms: a management-based classification system
- T. Pang, R. Maher, S. Gananadha, T. Hugh, J. Samra
- Medicine
- Surgical Endoscopy
- 12 February 2014
AbstractBackground
Peripancreatic pseudoaneurysms can arise in a number of different clinical settings but are associated mostly with pancreatitis and pancreatobiliary surgery. The aim of this study… Expand