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Global DNA methylation profiling reveals silencing of a secreted form of Epha7 in mouse and human germinal center B-cell lymphomas
Most human lymphomas originate from transformed germinal center (GC) B lymphocytes. While activating mutations and translocations of MYC, BCL2 and BCL6 promote specific GC lymphoma subtypes, otherExpand
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Nodular lymphocyte-predominant Hodgkin's disease associated with large-cell lymphoma: analysis of Ig gene rearrangements by V-J polymerase chain reaction.
The clonality of nodular lymphocyte-predominant Hodgkin's disease (NLPHD) and the relationship to composite or sequential large-cell lymphomas (LCLs) is poorly understood. Clonal Ig heavy-chain geneExpand
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Interferon-α induces dendritic cell differentiation of CML mononuclear cells in vitro and in vivo
The ability of interferon-α (IFN-α) to induce dendritic cell (DC) differentiation in chronic myeloid leukemia (CML) was evaluated. Peripheral blood mononuclear cells from CML patients cultured withExpand
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Interferon-alpha induces dendritic cell differentiation of CML mononuclear cells in vitro and in vivo.
The ability of interferon-alpha (IFN-alpha) to induce dendritic cell (DC) differentiation in chronic myeloid leukemia (CML) was evaluated. Peripheral blood mononuclear cells from CML patientsExpand
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Multiple myeloma: the cells of origin – A two-way street
Multiple myeloma results from an interplay between the monoclonal malignant plasma cells and supporting nonmalignant cells in the bone marrow. Recent studies suggest that the final transforming eventExpand
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Preserving two decades of healthcare gains for africa in the Covid-19 era.
: As Covid-19 restrictions upend the community bonds that have enabled African communities to thrive in the face of numerous challenges, it is vital that the gains made in community-based health careExpand
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Pancreas and Beta Islet Cell Transplantation - Evidence Base and Outcomes
From a humble experimental debut in 1966, pancreatic transplantation has undergone significant advances undoubtedly becoming the gold standard endocrine replacement therapy for diabetes in ourExpand
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Preserving 2 decades of healthcare gains for Africa in the coronavirus disease 2019 era
As coronavirus disease 2019 (Covid-19) restrictions upend the community bonds that have enabled African communities to thrive in the face of numerous challenges, it is vital that the gains made inExpand