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N(6)-Methyladenosine Modification in a Long Noncoding RNA Hairpin Predisposes Its Conformation to Protein Binding.
N(6)-Methyladenosine (m(6)A) is a reversible and abundant internal modification of messenger RNA (mRNA) and long noncoding RNA (lncRNA) with roles in RNA processing, transport, and stability.Expand
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The Japanese mutant Aβ (ΔE22-Aβ(1-39)) forms fibrils instantaneously, with low-thioflavin T fluorescence: seeding of wild-type Aβ(1-40) into atypical fibrils by ΔE22-Aβ(1-39).
The ΔE693 (Japanese) mutation of the β-amyloid precursor protein leads to production of ΔE22-Aβ peptides such as ΔE22-Aβ(1-39). Despite reports that these peptides do not form fibrils, here we showExpand
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Theoretical aspects of higher‐order truncations in solid‐state nuclear magnetic resonance
Recent experimental developments of high‐resolution NMR in solids (for example, double rotation and dynamic‐angle spinning) address the reduction of second‐order line broadening effects, particularlyExpand
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Phosphoantigen-induced conformational change of butyrophilin 3A1 (BTN3A1) and its implication on Vγ9Vδ2 T cell activation
Significance Gamma delta T cells, a group of immune cells that exhibit features from both innate and adaptive immunity, possess significant potential in clinical applications such as treatment ofExpand
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ELECTRICAL CHARACTERIZATION OF BATIO3 HETEROEPITAXIAL THIN FILMS BY HYDROTHERMAL SYNTHESIS
The electrical properties of hydrothermally grown epitaxial pseudocubic BaTiO 3 thin films formed on epitaxial electrode layers of SrRuO 3 on SrTiO 3 single crystal substrates have been evaluated byExpand
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Solid-state carbon-13 nuclear magnetic resonance of humic acids at high magnetic field strengths.
Use of solid-state 13C nuclear magnetic resonance (NMR) spectroscopy has become commonplace in studies of humic substances in soils and sediments, but when modern high-field spectrometers areExpand
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Soy addition improves the texture of microwavable par-baked pocket-type flat doughs
Microwavable baked goods are used frequently by the food industry to enrobe meat, vegetable, and sweet items for convenient meal delivery but suffer from poor texture upon microwave re-heating.Expand
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Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasis
BNip3 is a hypoxia‐inducible protein that targets mitochondria for autophagosomal degradation. We report a novel tumor suppressor role for BNip3 in a clinically relevant mouse model of mammaryExpand
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Fast acquisition of multi-dimensional spectra in solid-state NMR enabled by ultra-fast MAS.
The advantages offered by ultra-fast (>60 kHz) magic angle spinning (MAS) rotation for the study of biological samples, notably containing paramagnetic centers are explored. It is shown that optimalExpand
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Solid-state NMR characterization of pyrene-cuticular matter interactions.
One- and two-dimensional nuclear magnetic resonance (NMR) experiments were performed on Agave americana cutan and tomato cutin to examine the interactions between a hydrophobic pollutant, pyrene, andExpand
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