• Publications
  • Influence
The action of oxygen and oxygen at high pressure on inhibitory transmission
The effect of 100% oxygen at ambient pressure, 100% oxygen at 1.7 Atmospheres Absolute (ATA), 100% oxygen at 5.1 ATA, helium at 1.7 ATA and helium at 5.1 ATA on inhibitory synaptic transmission wasExpand
  • 21
  • 3
Interaction of Ca-channel blockers and high pressure at the crustacean neuromuscular junction
Exposure to high pressure causes a significant depression of synaptic transmission. We examined the effects of various Ca-channel blockers and their interaction with high pressure on excitatoryExpand
  • 19
  • 2
Changes in synaptic transmission produced by hydrogen peroxide.
The effect of hydrogen peroxide (H2O2) on excitatory and inhibitory synaptic transmission was studied at the lobster neuromuscular junction. H2O2 produced a dose dependent decrease in the amplitudeExpand
  • 33
  • 1
An electrophysiological analysis of oxygen and pressure on synaptic transmission
The effect of oxygen at high pressure (OHP), helium at 150 PSIG and 100% oxygen at ambient pressure on excitatory synaptic transmission was studied using the lobster walking leg neuromuscularExpand
  • 23
  • 1
Aminopyridines and sparteine as inhibitors of membrane potassium conductance: effects on Myxicola giant axons and the lobster neuromuscular junction.
The effects of the compounds 2-, 3- and 4-aminopyridine and sparteine on membrane conductance changes were examined using both voltage-clamped Myxicola axons and the lobster neuromuscular junction.Expand
  • 75
Protection from oxidation enhances the survival of cultured mesencephalic neurons
Oxidative stress has been linked to the destruction of dopaminergic neurons in the substantia nigra and may be a significant factor in both Parkinson's disease and MPTP toxicity. Using primaryExpand
  • 57
Blockade of hyperbaric oxygen induced seizures by excitatory amino acid antagonists.
The effectiveness of several excitatory amino acid antagonists to delay or block seizures induced by oxygen at high pressure was examined in mice. Of the antagonists tested, namely, L-proline,Expand
  • 21
Effect of pressure on [3H]GABA release by synaptosomes isolated from cerebral cortex.
High hydrostatic pressure has been shown to produce neurological changes in humans which manifest, in part, as tremor, myoclonic jerks, electroencephalographic changes, and convulsions. This clinicalExpand
  • 16
Cerebrovascular response to CO 2 during hyperthermia.
  • 11
The action of dantrolene sodium on the lobster neuromuscular junction.
Abstract 1. At a concentration of 2.3 to 3.1 × 10−5 M, dantrolene Na increased the frequency of stimulation required to elicit a visible muscle contraction from 7 stimuli/sec to a minimum of 25Expand
  • 2
...
1
2
3
4
...