Author pages are created from data sourced from our academic publisher partnerships and public sources.
Mechanical Stressing of Integrin Receptors Induces Enhanced Tyrosine Phosphorylation of Cytoskeletally Anchored Proteins*
- C. Schmidt, H. Pommerenke, F. Dürr, B. Nebe, J. Rychly
- Medicine, Biology
- The Journal of Biological Chemistry
- 27 February 1998
Physical forces play a fundamental role in the regulation of cell function in many tissues, but little is known about how cells are able to sense mechanical loads and realize signal transduction.… Expand
Calcium phosphate surfaces promote osteogenic differentiation of mesenchymal stem cells
- P. Müller, U. Bulnheim, +8 authors J. Rychly
- Medicine, Biology
- Journal of cellular and molecular medicine
- 13 August 2007
Although studies in vivo revealed promising results in bone regeneration after implantation of scaffolds together with osteogenic progenitor cells, basic questions remain how material surfaces… Expand
Tissue-like self-assembly in cocultures of endothelial cells and osteoblasts and the formation of microcapillary-like structures on three-dimensional porous biomaterials.
- R. Unger, A. Sartoris, +6 authors C. Kirkpatrick
- Materials Science, Medicine
- 1 September 2007
The survival and functioning of a bone biomaterial requires a rapid and stable vascularization after implantation. However, the mechanisms involved in the context of the complex healing… Expand
Stimulation of integrin receptors using a magnetic drag force device induces an intracellular free calcium response.
- H. Pommerenke, E. Schreiber, +4 authors J. Rychly
- Biology, Medicine
- European journal of cell biology
- 1 June 1996
Mechanical loading of cells is of fundamental relevance in physiological processes and induces several functional responses in cells. Integrins, a family of adhesion receptors, which are responsible… Expand
Adhesiveness of the free surface of a human endometrial monolayer for trophoblast as related to actin cytoskeleton.
Adhesiveness of the apical (free) plasma membrane of uterine epithelial cells for trophoblast is essential for the process of human embryo implantation. As epithelial cells are normally repellent,… Expand
The Mode of Mechanical Integrin Stressing Controls Intracellular Signaling in Osteoblasts
- H. Pommerenke, C. Schmidt, +4 authors J. Rychly
- Biology, Medicine
- Journal of bone and mineral research : the…
- 1 April 2002
Following the idea that integrin receptors function as mechanotransducers, we applied defined physical forces to integrins in osteoblastic cells using a magnetic drag force device to show how cells… Expand
Mechanical induction of beta 1-integrin-mediated calcium signaling in a hepatocyte cell line.
Mechanical stress influences growth, differentiation, and gene expression in a variety of cell types. It is believed that via extracellular matrix the mechanical stimulus is transmitted to integrin… Expand
Control of focal adhesion dynamics by material surface characteristics.
The mechanisms of cell adhesion to the extracellular matrix (ECM) which are of fundamental importance for function, survival, and growth of cells involve the formation of focal adhesions to… Expand
The influence of surface roughness of titanium on β1- and β3-integrin adhesion and the organization of fibronectin in human osteoblastic cells
Mechanisms of cell adhesion and extracellular matrix formation are primary processes in the interaction with the material surface of an implant which are controlled by integrin receptors. The aim of… Expand
Effects of selenium supplementation on immune parameters in chronic uraemic patients on haemodialysis.
- M. Bonomini, S. Forster, +5 authors A. Albertazzi
- Nephrology, dialysis, transplantation : official…
- 1 September 1995
BACKGROUND The involvement of selenium (Se) in immune response has been increasingly recognized, cell-mediated immunity being principally affected by Se deficiency. Blood Se levels in chronic uraemic… Expand