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The Genome of the Ctenophore Mnemiopsis leidyi and Its Implications for Cell Type Evolution
TLDR
The genome of the ctenophore the warty comb jelly or sea walnut, Mnemiopsis leidyi, is sequenced and it is concluded that c tenophores alone, not sponges or the clade consisting of both ctenphores and cnidarians, are the most basal extant animals. Expand
Genomic evidence for ameiotic evolution in the bdelloid rotifer Adineta vaga
TLDR
The genome of a bdelloid rotifer, Adineta vaga, is reported and it is shown that its structure is incompatible with conventional meiosis, and abundant evidence of gene conversion is found, which may limit the accumulation of deleterious mutations in the absence of meiosis. Expand
The cnidarian-bilaterian ancestor possessed at least 56 homeoboxes: evidence from the starlet sea anemone, Nematostella vectensis
TLDR
This work reports the first near-complete set of homeodomains from a basal (diploblastic) animal, Nematostella vectensis, which underwent extensive radiations prior to the evolutionary split between Cnidaria and Bilateria. Expand
Pre-Bilaterian Origins of the Hox Cluster and the Hox Code: Evidence from the Sea Anemone, Nematostella vectensis
TLDR
Phylogenetic, developmental, and genomic analyses on the cnidarian sea anemone Nematostella vectensis challenge recent claims that the Hox code is a bilaterian invention and that no “true” Hox genes exist in the phylum Cnidaria. Expand
The mid-developmental transition and the evolution of animal body plans
TLDR
It is proposed that a phylum may be defined as a collection of species whose gene expression at the mid-developmental transition is both highly conserved among them, yet divergent relative to other species. Expand
Rising starlet: the starlet sea anemone, Nematostella vectensis.
TLDR
The traits that make Nematostella exceptionally attractive as a model organism are explored, recent research demonstrating the utility of Nem atostella in several different contexts are summarized, and a number of developments likely to further increase that utility in the near future are highlighted. Expand
Genomic insights into Wnt signaling in an early diverging metazoan, the ctenophore Mnemiopsis leidyi
TLDR
Ctenophores show a minimal (but not obviously simple) complement of Wnt signaling components, which suggests that complex regulation of this secreted signaling pathway probably evolved later in animal evolution. Expand
Evolution of the TGF-β Signaling Pathway and Its Potential Role in the Ctenophore, Mnemiopsis leidyi
TLDR
The complexity and possible functions of this pathway in a member of one of the earliest branching metazoan phyla, the ctenophore Mnemiopsis leidyi, are investigated, suggesting roles in pharyngeal morphogenesis and comb row organization. Expand
The homeodomain complement of the ctenophore Mnemiopsis leidyi suggests that Ctenophora and Porifera diverged prior to the ParaHoxozoa
TLDR
The first glimpse of the first sequenced ctenophore genome is provided and it is suggested that Porifera and Ctenophora were the first two extant lineages to diverge from the rest of animals. Expand
StellaBase: The Nematostella vectensis Genomics Database
TLDR
StellaBase, the Nematostella vectensis Genomics Database, is a web-based resource that will facilitate desktop and bench-top studies of the starlet sea anemone and provides a framework for the integration of additional species-specific databases into CnidBase. Expand
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