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Ethanol extract of Adiantum capillus-veneris L. suppresses the production of inflammatory mediators by inhibiting NF-κB activation.
TLDR
The plant ethanolic extracts effectively suppressed PGE2, IL-6 and TNF release with an IC50 less than 50 μg/ml and displayed a cell-specific pattern on NF-κB gene transcription. Expand
Apoptosis induced by a new flavonoid in human hepatoma HepG2 cells involves reactive oxygen species-mediated mitochondrial dysfunction and MAPK activation.
TLDR
The cytotoxic effect of a new flavonoid, DEDC, which is a protoapigenone analog, was investigated in human hepatoma HepG2 cells and found that hepatoma cells were highly susceptible to D EDC in contrast with normal cells. Expand
In vitro and in vivo antitumor activity of Macrothelypteris torresiana and its acute/subacute oral toxicity.
TLDR
The overall results of this study suggest that the total flavonoid fraction from the roots of M. torresiana shows significant antitumor activity and represents a potential source of medicine for the treatment of cancer. Expand
DEDC, a new flavonoid induces apoptosis via a ROS-dependent mechanism in human neuroblastoma SH-SY5Y cells.
TLDR
Overall, this study shed light on the mechanism of action of DEDC and suggested more rational approaches to investigation and therapy for this childhood malignancy. Expand
Hypolipidemic and anti-inflammatory properties of Abacopterin A from Abacopteris penangiana in high-fat diet-induced hyperlipidemia mice.
TLDR
It is suggested that APA had hypolipidemic and anti-inflammatory properties through inhibiting NFκB expression, and reducing inflammatory response. Expand
In vitro and in vivo evaluation of the wound healing properties of Siegesbeckia pubescens.
TLDR
Experimental data revealed that the methanolic extract of SP displayed remarkable wound healing activity, corroborating its traditional use. Expand
Extraction and determination of some psychotropic drugs in urine samples using dispersive liquid-liquid microextraction followed by high-performance liquid chromatography.
TLDR
The proposed method was successfully applied to the real urine samples from two female patients under amitryptiline and clomipramine treatment, respectively and good linear behaviors over the investigated concentration ranges were obtained with the values of R(2)>0.998 for the target drugs. Expand
In vitro antiproliferative and antioxidant effects of urolithin A, the colonic metabolite of ellagic acid, on hepatocellular carcinomas HepG2 cells.
TLDR
It is suggested that UA could inhibit cell proliferation and reduce oxidative stress status in liver cancer, thus acting as a viably effective constituent for HCC prevention and treatment. Expand
Antioxidant and hepatoprotective activity of ethanol extract of Arachniodes exilis (Hance) Ching.
TLDR
The results indicate that this plant possesses potential antioxidant and hepatoprotective properties and has therapeutic potential for the treatment of liver diseases. Expand
Antioxidant, free radical scavenging, anti-inflammatory and hepatoprotective potential of the extract from Parathelypteris nipponica (Franch. et Sav.) Ching.
TLDR
This study provides a scientific basis for the ethnomedical claims that Parathelypteris nipponica (Franch. et Sav.) Ching is effective against inflammation and liver injury. Expand
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