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Detection of pharmaceutically active compounds in the rivers and tap water of the Madrid Region (Spain) and potential ecotoxicological risk.
The aim of this study was to determine the presence of 33 pharmaceutically active compounds in specific points of the main rivers of the Madrid Region as well as tap water samples from the metropolitan area of Madrid, and to report the highest concentration of the cytostatic ifosfamide, detected for the first time in Spain in surface water. Expand
Drugs of abuse and benzodiazepines in the Madrid Region (Central Spain): seasonal variation in river waters, occurrence in tap water and potential environmental and human risk.
Analyzes the seasonal variation of ten drugs of abuse, six metabolites and three benzodiazepines in surface waters from the Jarama and Manzanares Rivers in the Madrid Region, the most densely populated area in Spain to show that no toxic effects could be expected at the detected concentration level in tap water. Expand
Analysis of the presence of cardiovascular and analgesic/anti-inflammatory/antipyretic pharmaceuticals in river- and drinking-water of the Madrid Region in Spain.
An environmental surveillance system should be implemented to assess the continuous discharge of these pharmaceuticals and their possible ecotoxicological effects, and efforts to raise the awareness of the public about responsible use and the proper disposal of such substances at purpose-designated collection points should be increased. Expand
Seasonal variation of pharmaceutically active compounds in surface (Tagus River) and tap water (Central Spain)
Results might indicate that the PhACs analysed in this study undergo lower environmental degradation in winter than in summer, especially on thosePhACs that either because of an elevated consumption or an intrinsic chemical persistence are poorly degraded during winter months due to low temperatures and solar irradiation. Expand
Heterogeneous photo-Fenton treatment for the reduction of pharmaceutical contamination in Madrid rivers and ecotoxicological evaluation by a miniaturized fern spores bioassay.
This fact seemed to be related to the presence of toxicants in the water matrix, probably of inorganic nature, rather than the toxic effect of the studied pharmaceutical compounds, as revealed by the effective removal of these compounds and high TOC mineralization of photo-Fenton treatments. Expand
Does the presence of caffeine in the marine environment represent an environmental risk? A regional and global study.
Caffeine was found to be present at concentrations higher than the limit of quantification in 15 of the 23 samples analysed, with the highest seawater concentration being 857ngL-1 (the highest measured in seawater in Spain), indicating a high probability of adverse effects in the aquatic environment. Expand
Caffeine and paraxanthine in aquatic systems: Global exposure distributions and probabilistic risk assessment.
Caffeine, as well as its main metabolite (paraxanthine), were selected for this study, and it was determined that unacceptable environmental risk could be expected from chronic exposure to caffeine from effluent, surface water, and estuary water. Expand
Psychoactive pharmaceuticals and illicit drugs in coastal waters of North-Western Spain: Environmental exposure and risk assessment.
Monitoring of psychoactive pharmaceuticals and illicit drugs in the Rías Baixas coastal area of Northwestern Spain suggested that venlafaxine, citalopram, sertraline, and EDDP were present in concentrations potentially able to cause chronic effects in exposed organisms. Expand
Aquatic hazard assessment of MON 0818, a commercial mixture of alkylamine ethoxylates commonly used in glyphosate-containing herbicide formulations. Part 1: Species sensitivity distribution from
The sensitivity of 15 aquatic species, including primary producers, benthic invertebrates, cladocerans, mollusks, and fish, to MON 0818, a commercial surfactant mixture of polyoxyethylene tallowExpand
Temperature and Resource Availability May Interactively Affect Over-Wintering Success of Juvenile Fish in a Changing Climate
The results illustrate the importance of considering not only changes in temperature when predicting organism response to climate change but also food-web interactions, such as resource availability and predation, as exemplified by the finding that zooplankton over-winter biomass in the lake was not related to over- winter temperature. Expand