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Peripheral arterial vasodilation hypothesis: A proposal for the initiation of renal sodium and water retention in cirrhosis
TLDR
The stimulation of the renin‐angiotensin‐aldosterone system, vasopressin release and sympathetic nervous system associated with cirrhosis is not consonant with primary volume expansion, and favors the “overflow” hypothesis.
Increased risk of tumor seeding after percutaneous radiofrequency ablation for single hepatocellular carcinoma
TLDR
Radiofrequency ablation with cooled‐tip needle for HCC is associated with a high risk of neoplastic seeding, and has to be considered when selecting curative treatments for H CC or adjuvant therapies before liver transplantation.
Norfloxacin prevents spontaneous bacterial peritonitis recurrence in cirrhosis: Results of a double‐blind, placebo‐controlled trial
TLDR
Results indicate that long‐term selective intestinal decontamination with norfloxacin is an effective and safe measure to prevent spontaneous bacterial peritonitis recurrence caused by aerobic gram‐negative bacilli in cirrhosis.
Compensated cirrhosis: Natural history and prognostic factors
TLDR
To investigate the natural history of compensated cirrhosis, 293 consecutive patients without previous major complications were studied in terms of morbidity and survival and a prognostic index was constructed that allows calculation of the estimated survival probability.
Renal impairment after spontaneous bacterial peritonitis in cirrhosis: Incidence, clinical course, predictive factors and prognosis
TLDR
Renal impairment is the most important predictor of hospital mortality in cirrhotic patients with spontaneous bacterial peritonitis and hospital mortality during hospitalization, and it occurs mainly in patients with kidney failure before infection.
Natural history of untreated nonsurgical hepatocellular carcinoma: Rationale for the design and evaluation of therapeutic trials
TLDR
The outcome of nonsurgical HCC is not homogeneously grim and may be predicted by assessing the presence of symptoms and of an invasive tumoral pattern and Therapeutic trials should be designed and evaluated considering these characteristics.
Transarterial embolization versus symptomatic treatment in patients with advanced hepatocellular carcinoma: Results of a randomized, controlled trial in a single institution
TLDR
It is concluded that transarterial embolization has a marked antitumoral effect associated to a slower growth of the tumor, but it does not improve the survival of patients with nonsurgical HCC.
Tumor necrosis factor and interleukin‐6 in spontaneous bacterial peritonitis in cirrhosis: Relationship with the development of renal impairment and mortality
TLDR
The inflammatory response to the infection may be an important mechanism of renal impairment and the associated mortality in spontaneous bacterial peritonitis.
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