Repurposing diflunisal for familial amyloid polyneuropathy: a randomized clinical trial.
Among patients with familial amyloid polyneuropathy, the use of diflunisal compared with placebo for 2 years reduced the rate of progression of neurological impairment and preserved quality of life.
This article reviews the inherited and acquired amyloidoses that affect the peripheral nervous system including familialAmyloid polyneuropathy, and primary, secondary and senile amyloidsosis and emphasizes the clinical presentation of the neurologic aspects of these diseases.
Capsaicin 8% Patch in Painful Diabetic Peripheral Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Study.
Diagnosis and management of HIV-associated neuropathy.
HIV-related neurocognitive impairment in the HAART era
The nature of HIV-related neurocognitive impairment in the HAART era is addressed, including its etiology, pathology, appropriate diagnostic tools for clinical practice and research, and rational treatment approaches.
Predictors of new-onset distal neuropathic pain in HIV-infected individuals in the era of combination antiretroviral therapy
The associations with opioid use disorders and depression reinforce the view that the clinical expression of neuropathic pain with peripheral nerve disease is strongly influenced by neuropsychiatric factors.
Motor function declines over time in human immunodeficiency virus and is associated with cerebrovascular disease, while HIV-associated neurocognitive disorder remains stable
- Isabel M Elicer, D. Byrd, U. Clark, S. Morgello, J. Robinson-Papp
- Psychology, MedicineJournal of Neurovirology
- 25 April 2018
It is concluded that the HDMS is a valid measurement of motor dysfunction in HIV-infected patients and is associated with cognitive impairment and the presence of cerebrovascular disease.
The Quantitative Analgesic Questionnaire: A Tool to Capture Patient-Reported Chronic Pain Medication Use.
HIV-related neuropathy: current perspectives
Clinically, HIV DSP is characterized by a combination of signs and symptoms that include decreased deep tendon reflexes at the ankles and decreased sensation in the distal extremities as well as paresthesias, dysesthesias, and pain in a symmetric stocking–glove distribution.
Neuromuscular diseases associated with HIV‐1 infection
The following HIV‐associated conditions are reviewed: distal symmetric polyneuropathy; inflammatory demyelinating polyne Neuropathy; mononeuropathy multiplex; autonomic neuropathy; progressive polyradiculopathy due to cytomegalovirus; herpes zoster; myopathy; and other, rarer disorders.