In observational studies with exposures or treatments that vary over time, standard approaches for adjustment of confounding are biased when there exist time-dependent confounders that are also… Expand

A graphical approach to the identification and computation of causal parameters in mortality studies with sustained exposure periods is offered and an adverse effect of arsenic exposure on all-cause and lung cancer mortality which standard methods fail to detect is found.Expand

Abstract In applied problems it is common to specify a model for the conditional mean of a response given a set of regressors. A subset of the regressors may be missing for some study subjects either… Expand

We revisit the classic semiparametric problem of inference on a low dimensional parameter θ_0 in the presence of high-dimensional nuisance parameters η_0. We depart from the classical setting by… Expand

The results of simulation studies are presented which demonstrate that the finite sample performance of DR estimators is as impressive as theory would predict and the proposed method is applied to a cardiovascular clinical trial.Expand

It is shown that adjustment for the intermediate variable, which is the most common method of estimating direct effects, can be biased, and that, even in a randomized crossover trial of exposure, direct and indirect effects cannot be separated without special assumptions.Expand

A Unified Approach for Causal Inference andcensored Data is presented, which combines cross-sectional data and Right Censored Data Combined to form a single corpus ofcensored data.Expand

It is estimated that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures, and public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.Expand

The marginal structural Cox proportional hazards model is described and used to estimate the causal effect of zidovudine on the survival of human immunodeficiency virus-positive men participating in the Multicenter AIDS Cohort Study.Expand

Abstract We propose a class of inverse probability of censoring weighted estimators for the parameters of models for the dependence of the mean of a vector of correlated response variables on a… Expand