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International study of the prevalence and outcomes of infection in intensive care units.
CONTEXT Infection is a major cause of morbidity and mortality in intensive care units (ICUs) worldwide. However, relatively little information is available about the global epidemiology of suchExpand
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Epidemiology and outcomes of ventilator-associated pneumonia in a large US database.
OBJECTIVES To evaluate risk factors for ventilator-associated pneumonia (VAP), as well as its influence on in-hospital mortality, resource utilization, and hospital charges. DESIGN RetrospectiveExpand
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Intensive care adult patients with severe respiratory failure caused by Influenza A (H1N1)v in Spain
IntroductionPatients with influenza A (H1N1)v infection have developed rapidly progressive lower respiratory tract disease resulting in respiratory failure. We describe the clinical and epidemiologicExpand
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Pneumonia in intubated patients: role of respiratory airway care.
In order to assess potential risk factors for pneumonia within the first 8 d of ventilation, we studied 83 consecutive intubated patients undergoing continuous aspiration of subglottic secretionsExpand
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DALI: defining antibiotic levels in intensive care unit patients: are current β-lactam antibiotic doses sufficient for critically ill patients?
BACKGROUND Morbidity and mortality for critically ill patients with infections remains a global healthcare problem. We aimed to determine whether β-lactam antibiotic dosing in critically ill patientsExpand
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Continuous Aspiration of Subglottic Secretions in Preventing Ventilator-Associated Pneumonia
Nosocomial pneumonia develops in 0.5 to 1 patient per 100 hospital admissions and is associated with high morbidity and mortality [1, 2]. Mechanically ventilated patients have a high risk forExpand
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A clinical algorithm to diagnose invasive pulmonary aspergillosis in critically ill patients.
RATIONALE The clinical relevance of Aspergillus-positive endotracheal aspirates in critically ill patients is difficult to assess. OBJECTIVES We externally validate a clinical algorithm toExpand
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Clinical cure and survival in Gram-positive ventilator-associated pneumonia: retrospective analysis of two double-blind studies comparing linezolid with vancomycin
ObjectiveTo assess the effect of baseline variables, including treatment, on clinical cure and survival rates in patients with Gram-positive, ventilator-associated pneumonia (VAP).DesignRetrospectiveExpand
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Oral care practices in intensive care units: a survey of 59 European ICUs
ObjectiveTo explore the type and frequency of oral care practices in European ICUs and the attitudes, beliefs, and knowledge of health care workers.DesignAn anonymous questionnaire was distributed toExpand
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Linezolid vs vancomycin: analysis of two double-blind studies of patients with methicillin-resistant Staphylococcus aureus nosocomial pneumonia.
OBJECTIVE To assess the effect of baseline variables, including treatment, on outcome in patients with nosocomial pneumonia due to methicillin-resistant Staphylococcus aureus (MRSA). DESIGNExpand
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