• Publications
  • Influence
A Subset of TAFIIs Are Integral Components of the SAGA Complex Required for Nucleosome Acetylation and Transcriptional Stimulation
A number of transcriptional coactivator proteins have been identified as histone acetyltransferase (HAT) proteins, providing a direct molecular basis for the coupling of histone acetylation andExpand
  • 414
  • 33
The multifunctional Ccr4-Not complex directly promotes transcription elongation.
The Ccr4-Not complex has been implicated in the control of multiple steps of mRNA metabolism; however, its functions in transcription remain ambiguous. The discovery that Ccr4/Pop2 is the majorExpand
  • 141
  • 19
  • PDF
Transcription activation in cells lacking TAFIIs
THE general transcription factor TFIID is composed of the TATA-box-binding protein (TBP) and a set of TBP-associated factors (TAFIIs) (ref. 1). In vitro, TAFIIs are required for activatedExpand
  • 244
  • 18
Functional antagonism between RNA polymerase II holoenzyme and global negative regulator NC2 in vivo.
Activation of eukaryotic class II gene expression involves the formation of a transcription initiation complex that includes RNA polymerase II, general transcription factors, and SRB components ofExpand
  • 68
  • 16
Ccr4-Not complex: the control freak of eukaryotic cells
The purpose of this review is to provide an analysis of the latest developments on the functions of the carbon catabolite-repression 4-Not (Ccr4-Not) complex in regulating eukaryotic gene expression.Expand
  • 135
  • 12
Yeast TAF(II)90 is required for cell-cycle progression through G2/M but not for general transcription activation.
The RNA polymerase II general transcription factor TFIID is a multisubunit complex comprising TATA-box binding protein and associated factors (TAFIIs). In vitro experiments have suggested that TAFIIsExpand
  • 142
  • 9
H9, H10, and H11 compose a cluster of Hessian fly-resistance genes in the distal gene-rich region of wheat chromosome 1AS
H9, H10, and H11 are major dominant resistance genes in wheat, expressing antibiosis against Hessian fly [(Hf) Mayetiola destructor (Say)] larvae. Previously, H9 and H10 were assigned to chromosomeExpand
  • 55
  • 9
  • PDF
Ssn6-Tup1 Regulates RNR3 by Positioning Nucleosomes and Affecting the Chromatin Structure at the Upstream Repression Sequence*
  • B. Li, J. Reese
  • Medicine, Biology
  • The Journal of Biological Chemistry
  • 7 September 2001
The DNA damage inducible gene ribonucleotide reductase (RNR3) is regulated by a transcriptional repression mechanism by the recruitment of the Ssn6-Tup1 corepressor complex to its promoter by theExpand
  • 80
  • 7
Histone Deacetylases RPD3 and HOS2 Regulate the Transcriptional Activation of DNA Damage-Inducible Genes
ABSTRACT DNA microarray and genetic studies of Saccharomyces cerevisiae have demonstrated that histone deacetylases (HDACs) are required for transcriptional activation and repression, but theExpand
  • 97
  • 7
SWI/SNF-dependent chromatin remodeling of RNR3 requires TAF(II)s and the general transcription machinery.
Gene expression requires the recruitment of chromatin remodeling activities and general transcription factors (GTFs) to promoters. Whereas the role of activators in recruiting chromatin remodelingExpand
  • 76
  • 7
  • PDF