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Nanomechanical analysis of cells from cancer patients.
Change in cell stiffness is a new characteristic of cancer cells that affects the way they spread. Despite several studies on architectural changes in cultured cell lines, no ex vivo mechanical… Expand
Hydrodynamic stretching of single cells for large population mechanical phenotyping
- D. Gossett, H. Tse, +6 authors D. Di Carlo
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 30 April 2012
Cell state is often assayed through measurement of biochemical and biophysical markers. Although biochemical markers have been widely used, intrinsic biophysical markers, such as the ability to… Expand
Identification and characterization of repopulating spermatogonial stem cells from the adult human testis.
BACKGROUND This study was conducted to identify and characterize repopulating spermatogonial stem cells (SSCs) in the adult human testes. METHODS Testes biopsies from obstructive azoospermic… Expand
Solitary Fibrous Tumor
BACKGROUND Initially described as a pleural tumor, solitaryfibrous tumor of the parotid gland (SFT) is rare and has been reported at a wide range ofanatomic sites. Although cases of SFT arising in… Expand
AFM-based analysis of human metastatic cancer cells.
- S. E. Cross, Yu-sheng Jin, Julianne Tondre, R. Wong, J. Rao, J. Gimzewski
- Materials Science, Medicine
- 12 August 2008
Recently biomechanics of cancer cells, in particular stiffness or elasticity, has been identified as an important factor relating to cancer cell function, adherence, motility, transformation and… Expand
Gene expression in epithelial ovarian carcinoma
- D. Matei, T. Graeber, R. L. Baldwin, B. Karlan, J. Rao, D. D. Chang
- Biology, Medicine
- 12 September 2002
We analysed the mRNA levels corresponding to 12 600 transcripts in primary cultures of ovarian epithelial cells derived from nine normal ovaries and 21 epithelial ovarian carcinoma. The class… Expand
Green tea extract and (−)-epigallocatechin-3-gallate inhibit hypoxia- and serum-induced HIF-1α protein accumulation and VEGF expression in human cervical carcinoma and hepatoma cells
Green tea extract and its major component (−)-epigallocatechin-3-gallate (EGCG) exhibit antiangiogenic activities in various experimental tumor models. A growing body of evidence has established that… Expand
Macrophage inhibitory cytokine 1 (MIC-1/GDF15) as a novel diagnostic serum biomarker in pancreatic ductal adenocarcinoma
BackgroundMacrophage inhibitory cytokine 1 (MIC-1/GDF15) has been identified as a potential novel biomarker for detection of pancreatic cancer (PCa). However, the diagnostic value of serum MIC-1 for… Expand
Effect of saw palmetto soft gel capsule on lower urinary tract symptoms associated with benign prostatic hyperplasia: a randomized trial in Shanghai, China.
PURPOSE We determined the effect of Prostataplex in men with lower urinary tract symptoms associated with benign prostatic hyperplasia. MATERIALS AND METHODS A total of 92 Chinese men between 49… Expand
Associations between NBS1 polymorphisms, haplotypes and smoking-related cancers.
Constituents of tobacco smoke can cause DNA double-strand breaks (DSBs), leading to tumorigenesis. The NBS1 gene product is a vital component in DSB detection and repair, thus genetic variations may… Expand