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Prevalence of carpal tunnel syndrome in a general population.
TLDR
About 1 in 5 symptomatic subjects would be expected to have CTS based on clinical examination and electrophysiologic testing, which indicates symptoms of pain, numbness, and tingling in the hands are common in the general population. Expand
Treatment for acute anterior cruciate ligament tear: five year outcome of randomised trial
TLDR
In this first high quality randomised controlled trial with minimal loss to follow-up, a strategy of rehabilitation plus early ACL reconstruction did not provide better results at five years than an initial rehabilitation with the option of having a later ACL reconstruction. Expand
A randomized trial of treatment for acute anterior cruciate ligament tears.
TLDR
In young, active adults with acute ACL tears, a strategy of rehabilitation plus early ACL reconstruction was not superior to a strategyof rehabilitation plus optional delayed ACL reconstruction, but the latter strategy substantially reduced the frequency of surgical reconstructions. Expand
Efficacy and safety of balloon kyphoplasty compared with non-surgical care for vertebral compression fracture (FREE): a randomised controlled trial
TLDR
The findings suggest that balloon kyphoplasty is an effective and safe procedure for patients with acute vertebral fractures and will help to inform decisions regarding its use as an early treatment option. Expand
Relapse rate, renal survival, and cancer morbidity in patients with Wegener's granulomatosis or microscopic polyangiitis with renal involvement.
TLDR
Improved therapy and medical care are needed for patients with WG and MPA and an 11-fold increase in risk for bladder cancer in patients treated with cyclophosphamide for at least 12 mo is found. Expand
Alcohol, tobacco and breast cancer – collaborative reanalysis of individual data from 53 epidemiological studies, including 58 515 women with breast cancer and 95 067 women without the disease
TLDR
In conclusion, smoking has little or no independent effect on the risk of developing breast cancer; the effect of alcohol on breast cancer needs to be interpreted in the context of its beneficial effects, in moderation, on cardiovascular disease and its harmful effects on cirrhosis. Expand
Breast cancer and hormone replacement therapy: collaborative reanalysis of data from 51 epidemiological studies of 52 705 women with breast cancer and 108 411 women without breast cancer
TLDR
Of the many factors examined that might affect the relation between breast cancer risk and use of HRT, only a woman's weight and body-mass index had a material effect: the increase in the relative risk of breast cancer diagnosed in women using HRT and associated with long durations of use in current and recent users was greater for women of lower than of higher weight or body- mass index. Expand
Breast cancer and breastfeeding: collaborative reanalysis of individual data from 47 epidemiological studies in 30 countries, including 50 302 women with breast cancer and 96 973 women without the
TLDR
The longer women breast feed the more they are protected against breast cancer, and the lack of or short lifetime duration of breastfeeding typical of women in developed countries makes a major contribution to the high incidence of breast cancer in these countries. Expand
Determinants of survival in liver resection for colorectal secondaries
TLDR
It is concluded that resection for liver colorectal secondaries is indicated when there are less than four liver tumours, even if bilateral, no extrahepatic disease is present, and a resection margin of at least 10 mm can be obtained. Expand
Breast cancer and hormonal contraceptives: collaborative reanalysis of individual data on 53 297 women with breast cancer and 100 239 women without breast cancer from 54 epidemiological studies
TLDR
The relation observed between breast cancer risk and hormone exposure is unusual, and it is not possible to infer from these data whether it is due to an earlier diagnosis of breast cancer in ever-users, the biological effects of hormonal contraceptives, or a combination of reasons. Expand
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