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Genic capture and resolving the lek paradox.
The genic capture hypothesis offers a resolution to the question of how genetic variation in male sexually selected traits is maintained in the face of strong female preferences. The hypothesis isExpand
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New generation sequencers as a tool for genotyping of highly polymorphic multilocus MHC system
Accurate genotyping of complex systems, such as the major histocompatibility complex (MHC) often requires simultaneous analysis of multiple co‐amplifying loci. Here we explore the utility of theExpand
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454 sequencing reveals extreme complexity of the class II Major Histocompatibility Complex in the collared flycatcher
BackgroundBecause of their functional significance, the Major Histocompatibility Complex (MHC) class I and II genes have been the subject of continuous interest in the fields of ecology, evolutionExpand
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Does reduced MHC diversity decrease viability of vertebrate populations?
Abstract Loss of genetic variation may render populations more vulnerable to pathogens due to inbreeding depression and depletion of variation in genes responsible for immunity againstExpand
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Effects of an MHC‐DRB genotype and allele number on the load of gut parasites in the bank vole Myodes glareolus
The major histocompatibility complex (MHC) genes code for the proteins responsible for pathogen recognition. The MHC class II DRB gene is multiplicated in the bank vole, Myodes glareolus, withExpand
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MHC diversity in bottlenecked populations: a simulation model
The depletion of variation at MHC loci, which play a crucial role in pathogen recognition, has been postulated to be one of important extinction risk factors for endangered populations. Thus, it isExpand
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Evaluation of two approaches to genotyping major histocompatibility complex class I in a passerine—CE‐SSCP and 454 pyrosequencing
Genes of the highly dynamic major histocompatibility complex (MHC) are directly linked to individual fitness and are of high interest in evolutionary ecology and conservation genetics. GeneExpand
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Effectiveness of sexual selection in removing mutations induced with ionizing radiation
Because of the production of males, sexual populations are expected to incur a 50% cost in potential growth rate. However, theory predicts that sexual competition between males can compensate forExpand
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Sequence diversity of the MHC DRB gene in the Eurasian beaver (Castor fiber)
Major histocompatibility complex (MHC) genes, coding molecules which play an important role in immune response, are the most polymorphic genes known in vertebrates. However, MHC polymorphism in someExpand
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jMHC: software assistant for multilocus genotyping of gene families using next‐generation amplicon sequencing
Genotyping of multilocus gene families, such as the major histocompatibility complex (MHC), may be challenging because of problems with assigning alleles to loci and copy number variation amongExpand
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