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Serum concentrations of DKK‐1 correlate with the extent of bone disease in patients with multiple myeloma
Objectives:  Lytic bone disease is a hallmark of multiple myeloma (MM) and is caused by osteoclast activation and osteoblast inhibition. Secretion of Dickkopf (DKK)‐1 by myeloma cells is a major
Phenotyping Established Chronic Lung Allograft Dysfunction Predicts Extracorporeal Photopheresis Response in Lung Transplant Patients
TLDR
Proposed CLAD phenotypes require refinement, but appear to predict the likelihood of ECP response, and ECP appears an effective second line treatment in CLAD patients progressing under azithromycin.
[Pulmonary manifestations of inflammatory bowel disease].
TLDR
Pulmonary disease is a rare complication of inflammatory bowel disease and several other manifestations have been described, and typical symptoms are productive cough, chest pain, and progressive dyspnea.
Burden and trends of hospitalisations associated with pulmonary non-tuberculous mycobacterial infections in Germany, 2005–2011
TLDR
Evidence is provided of a changing epidemiology of PNTM infections and highlights emerging clinical implications in Germany, where COPD is currently the most important associated condition.
Bronchiectasis in Germany: a population-based estimation of disease prevalence
TLDR
The aim of the present study was to estimate the overall prevalence of bronchiectasis in Germany over a 1-year period from a representative sample of routine statutory health insurance claim data, with special attention paid to the distribution of age and sex, and the site of healthcare provision.
Bronchiectasis-Associated Hospitalizations in Germany, 2005–2011: A Population-Based Study of Disease Burden and Trends
TLDR
Evidence of a changing epidemiology and a steadily increasing prevalence of bronchiectasis-associated hospitalizations in Germany is provided, which confirms the diversity of bronchitis-associated conditions and the possible association between bronchiECTasis and COPD.
Synergistic interaction of the histone deacetylase inhibitor SAHA with the proteasome inhibitor bortezomib in mantle cell lymphoma
TLDR
The effects of combined treatment with the proteasome inhibitor bortezomib and the histone deacetylase inhibitor (HDACi) suberoylanilide hydroxamic acid (SAHA) on MCL are evaluated.
The EMBARC European Bronchiectasis Registry: protocol for an international observational study
TLDR
The European Bronchiectasis Registry aims to make a major contribution to understanding the natural history of the disease, as well as guiding evidence-based decision making and facilitating large randomised controlled trials.
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