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Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases.
- J. R. Somoza, R. Skene, L. Tari
- BiologyStructure
- 1 July 2004
Visualizing ATP-dependent RNA translocation by the NS3 helicase from HCV.
- T. Appleby, R. Anderson, J. R. Somoza
- BiologyJournal of molecular biology
- 4 February 2011
Clinical targeting of HIV capsid protein with a long-acting small molecule
TLDR
Structural and kinetic analysis of Escherichia coli GDP-mannose 4,6 dehydratase provides insights into the enzyme's catalytic mechanism and regulation by GDP-fucose.
- J. R. Somoza, S. Menon, F. Sullivan
- Chemistry, BiologyStructure
- 1 February 2000
Structural, Biochemical, and Biophysical Characterization of Idelalisib Binding to Phosphoinositide 3-Kinase δ*
- J. R. Somoza, David Koditek, M. Mcgrath
- Biology, ChemistryThe Journal of Biological Chemistry
- 28 January 2015
TLDR
Crystal structure of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from the protozoan parasite Tritrichomonas foetus.
- J. R. Somoza, M. Chin, P. Focia, C. Wang, R. Fletterick
- Biology, ChemistryBiochemistry
- 4 June 1996
TLDR
Structural basis for unique mechanisms of folding and hemoglobin binding by a malarial protease.
- Stephanie X. Wang, K. Pandey, J. McKerrow
- Biology, MedicineProceedings of the National Academy of Sciences…
- 1 August 2006
TLDR
The taste-active regions of monellin, a potently sweet protein.
- J. R. Somoza, J. Cho, S. Kim
- BiologyChemical senses
- 1 February 1995
TLDR
Crystal structure of human cathepsin V.
- J. R. Somoza, H. Zhan, M. Mcgrath
- Biology, ChemistryBiochemistry
- 21 September 2000
TLDR
Crystal structure of Tritrichomonas foetus inosine-5'-monophosphate dehydrogenase and the enzyme-product complex.
TLDR
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