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Structure-specific DNA cleavage by 5' nucleases.
Many processes, such as DNA replication, recombination and repair, produce branched DNA structures. These bifurcated molecules are trimmed by a group of homologous 5'-3' exonucleases (also known as… Expand
Identification and eradication of a denatured DNA isolated during alkaline lysis-based plasmid purification procedures.
Many plasmid isolation procedures use strongly alkaline conditions in the initial stages to facilitate lysis of the host bacteria. We demonstrate that such procedures can give rise to a minor but… Expand
A method for enhancing the transfection efficiency of minipreps obtained from plasmid cDNA libraries.
Viral polymerase-associated 5'-->3'-exonucleases: expression, purification, and uses.
- J. R. Sayers
- Chemistry, Medicine
- Methods in enzymology
Unexpected Active Site in Trypanosoma brucei Flap Endonuclease
OR03-1 Development of a platform technology to generate long-acting protein therapeutics
Who gives an iota about DNA repair?
Abstract The Biochemical Society colloquium on New Frontiers in DNA Repair was held on 19–20 December 2000 in Sussex, UK.
Acres of antibodies: the future of recombinant biomolecule production?
- J. R. Sayers
- Biology, Medicine
- Trends in biotechnology
- 1 November 2001
The Cambridge Healthtech Institute's second international conference entitled "Recombinant Therapeutics: Antibodies and Biomolecules" was held in Baltimore, MD, USA, 30 May-1 June 2001.