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Chagas disease: a new worldwide challenge
Endemic Chagas disease began as a neglected disease of poor, rural and forgotten populations. Its spread from Latin America to non-endemic countries is a new worldwide challenge, say Jose RodriguesExpand
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Emerging Chagas disease in Amazonian Brazil.
In the Amazon Basin, Trypanosoma cruzi infection is enzootic, involving a variety of wild mammals and at least 10 of the 16 reported silvatic triatomine bug species. Human cases of Chagas disease areExpand
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Epidemiology, control and surveillance of Chagas disease: 100 years after its discovery.
Chagas disease originated millions of years ago as an enzootic infection of wild animals and began to be transmitted to humans as an anthropozoonosis when man invaded wild ecotopes. While evidence ofExpand
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Chagas disease: what is known and what is needed--a background article.
  • J. R. Coura
  • Biology, Medicine
  • Memorias do Instituto Oswaldo Cruz
  • 30 October 2007
Chagas disease began millions of years ago as an enzootic disease of wild animals and started to be transmitted to man accidentally in the form of an anthropozoonosis when man invaded wild ecotopes.Expand
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Immunoblot assay using excreted-secreted antigens of Trypanosoma cruzi in serodiagnosis of congenital, acute, and chronic Chagas' disease.
Immunoblotting with trypomastigote excreted-secreted antigens (TESA blot) of Trypanosoma cruzi was evaluated as a method for diagnosis of chronic and acute phases as well as congenital (in newbornExpand
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Chagas disease: 100 years after its discovery. A systemic review.
Although Chagas disease was only discovered in 1909, it began millions of years ago as an enzootic disease among wild animals. Its transmission to man began accidentally as an anthropozoonosis whenExpand
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A mini-exon multiplex polymerase chain reaction to distinguish the major groups of Trypanosoma cruzi and T. rangeli in the Brazilian Amazon.
0. Fernandesi*3, S. S. Santos’, E. CupoUlo’, B. Mendonga’, R. Derre3, A. C. V. Junqueira’, L. C. Santos’, N. R. Sturm4, R. l3. NaifP, T. V. Barret’, Il. A. Campbell4 and J. R. Coura’ ‘Department ofExpand
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Brazilian isolates of Trypanosoma cruzi from humans and triatomines classified into two lineages using mini-exon and ribosomal RNA sequences.
Traditional molecular and biochemical methods, such as schizodeme analysis, karyotyping, DNA fingerprinting, and enzyme electrophoretic profiles, have shown a large variability among TrypanosomaExpand
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Molecular epidemiology of American trypanosomiasis in Brazil based on dimorphisms of rRNA and mini-exon gene sequences.
American trypanosomiasis is transmitted in nature via a sylvatic cycle, where Trypanosoma cruzi interacts with wild triatomines and mammalian reservoirs, or via a domestic cycle where the parasiteExpand
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A new challenge for malaria control in Brazil: asymptomatic Plasmodium infection--a review.
The evolution of malaria in Brazil, its morbidity, the malaria control programs, and the new challenges for these programs in the light of the emergence of asymptomatic infection in the Amazon regionExpand
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