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Budesonide/formoterol for maintenance and relief in uncontrolled asthma vs. high-dose salmeterol/fluticasone.
BACKGROUND Budesonide/formoterol maintenance and reliever therapy (Symbicort SMART) improves asthma control compared with fixed-dose inhaled corticosteroid/long-acting beta(2)-agonist (ICS/LABA)Expand
Understanding patient sensitization profiles in complex pollen areas: a molecular epidemiological study
Background:  Allergy diagnosis in patients exposed to multiple pollen species is complex and misdiagnosis is often a cause for unsuccessful specific immunotherapy.
Rheumatic manifestations in 556 patients with human immunodeficiency virus infection.
We studied in retrospect the rheumatic manifestations of 556 patients with human immunodeficiency virus (HIV) infection. Eighty percent were men. Eighty-six percent were intravenous drug abusersExpand
High Levels of Olea europaea Pollen and Relation with Clinical Findings
Background: Olea europaea pollen is an important cause of seasonal allergic rhinitis and bronchial asthma in southern Spain. For patients allergic to grass pol– len the critical concentration ofExpand
Association of thromboxane A1 synthase (TBXAS1) gene polymorphism with acute urticaria induced by nonsteroidal anti-inflammatory drugs.
8. Martin L, Raison-Peyron N, N€othen MM, Cichon S, Drouet C. Hereditary angioedema with normal C1 inhibitor gene in a family with affected women and men is associated with the p.Thr328Lys mutationExpand
Anaphylaxis after ingestion of wheat flour contaminated with mites.
BACKGROUND Anaphylaxis after ingestion of flours contaminated with mites has been recently reported. OBJECTIVE The study was designed to determine whether four-induced reactions in the absence ofExpand
LTC4-synthase A-444C polymorphism: lack of association with NSAID-induced isolated periorbital angioedema in a Spanish population.
BACKGROUND The mechanism of nonsteroidal anti-inflammatory drug (NSAID)-induced reactions is unknown. However, strong evidence supports the hypothesis of an enhanced production ofExpand
Association of HLA-DR11 with the anaphylactoid reaction caused by nonsteroidal anti-inflammatory drugs.
BACKGROUND Several HLA alleles have been associated with asthma induced by nonsteroidal anti-inflammatory drugs (NSAIDs). The existence of HLA markers linked to other NSAID-induced reactions, such asExpand
Intolerance to nonsteroidal antiinflammatory drugs: results of controlled drug challenges in 98 patients.
BACKGROUND Controlled oral challenge is the only definitive way to detect the different clinical manifestations of intolerance to nonsteroidal antiinflammatory drugs (NSAIDs). OBJECTIVE This studyExpand
EU Forum: The CREATE Project: development of certified reference materials for allergenic products and validation of methods for their quantification
Allergen extracts have been used for diagnosis and treatment of allergy for around 100 years. During the second half of 20th century, the notion increasingly gained foothold that accurateExpand