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Relation among serum and tissue concentrations of lutein and zeaxanthin and macular pigment density.
Significant negative correlations were found between adipose tissue lutein concentrations and MP for women, but a significant positive relation was found for men, suggesting sex differences in luteIn metabolism may be an important factor in tissue interactions and in determining MP density.
Effect of miR-203 expression on myocardial fibrosis.
Over-expression of miR-203 in mouse cardiomyocytes significantly decreased the expression levels of TGF-β1, CTGF, and FN, which might be used as a detection index for prediction of fibrosis.
Expression of c‐myc in human colonic tissue in response to β‐carotene supplementation
Dietary supplementation with β‐carotene at 30 mg/day results in an increased serum trans‐retinoic acid concentration in patients with a prior colonic polyp and an increase in c‐myc expression after supplementation was observed in 6 of 12 subjects, but 5 of these 6 subjects had decreased total serum retinoic Acid concentration and 4 had decreased ATRA concentration.
Expression of c-myc in human colonic tissue in response to beta-carotene supplementation.
It is concluded that c-myc expression is not correlated with ATRA, 13-cRA, or total retinoic acid concentration in vivo and that increased serum retinic acid secondary to increased tissue beta-carotene is not sufficient to activate c- myc transcription.
Determination of carcinogenic potency of alkytoxynol-741 (AP-741) by rat peritoneal cell cultures.