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RNA-seq based identification and mutant validation of gene targets related to ethanol resistance in cyanobacterial Synechocystis sp. PCC 6803
RNA-Seq based global transcriptomic analysis provided a comprehensive view of cellular response to ethanol exposure, and provided a list of gene targets for engineering ethanol tolerance in cyanobacterium Synechocystis.
Quantitative proteomics reveals dynamic responses of Synechocystis sp. PCC 6803 to next-generation biofuel butanol.
Integrated proteomic and transcriptomic analysis reveals novel genes and regulatory mechanisms involved in salt stress responses in Synechocystis sp. PCC 6803
- J. Qiao, S. Huang, Rigen Te, Jiangxin Wang, Lei Chen, Weiwen Zhang
- BiologyApplied Microbiology and Biotechnology
- 8 August 2013
Gene knockout and comparative growth analysis demonstrated that four genes were involved in salt tolerance in Synechocystis, and a complementary proteome and transcriptome analysis showed that concordance between protein abundances and their corresponding mRNAs varied significantly between various gene–protein pairs, indicating divergent regulation of transcriptional and post-transcriptional processes during salt stress adaptation in SynchocyStis.
Extraction, purification and antibacterial activities of a polysaccharide from spent mushroom substrate.
Conversion of spent mushroom substrate to biofertilizer using a stress-tolerant phosphate-solubilizing Pichia farinose FL7.
Quantitative iTRAQ LC-MS/MS proteomics reveals metabolic responses to biofuel ethanol in cyanobacterial Synechocystis sp. PCC 6803.
This study provided the first comprehensive view of the complicated molecular mechanisms against ethanol stress and also provided a list of potential gene targets for further engineering ethanol tolerance in Synechocystis PCC 6803.
Metabolic engineering of Escherichia coli for production of salvianic acid A via an artificial biosynthetic pathway.
Proteomic analysis reveals resistance mechanism against biofuel hexane in Synechocystis sp. PCC 6803
- Jie Liu, Lei Chen, Jiangxin Wang, J. Qiao, Weiwen Zhang
- BiologyBiotechnology for Biofuels
- 7 September 2012
The study provided the first comprehensive view of the complicated molecular mechanism employed by cyanobacterial model species, Synechocystis to defend against hexane stress and provided a list of potential targets to engineer SyneChocyst is against hexanes stress.
Combined alkali and acid pretreatment of spent mushroom substrate for reducing sugar and biofertilizer production.
Integrated OMICS guided engineering of biofuel butanol-tolerance in photosynthetic Synechocystis sp. PCC 6803
The integrated OMICS analysis provided a comprehensive view of the complicated molecular mechanisms employed by Synechocystis sp.