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Altered corticostriatal functional connectivity in obsessive-compulsive disorder.
TLDR
This study directly supports the hypothesis that OCD is associated with functional alterations of brain corticostriatal networks, as measured from coherent spontaneous fluctuations in the blood oxygenation level-dependent signal. Expand
Mapping structural brain alterations in obsessive-compulsive disorder.
TLDR
The structural brain alterations detected in the magnetic resonance images of a large series of patients with obsessive-compulsive disorder (OCD) are described using imaging procedures that allow the evaluation of volume changes throughout the brain. Expand
Cerebral lateralization of language in normal left-handed people studied by functional MRI
TLDR
Silent word generation lateralizes to the left cerebral hemisphere in both handedness groups, but right-hemisphere participation is frequent in normal left-handed subjects. Expand
Time course and functional neuroanatomy of speech segmentation in adults
TLDR
Findings from the present investigation are interpreted as evidence for the existence of an auditory-motor interface that is responsible for isolating possible candidate words when learning a new language in adults. Expand
Leuko-araiosis on magnetic resonance imaging and speed of mental processing.
TLDR
It is found that leuko-araiosis was related to performance on tasks measuring the speed of information processing and, in particular, on those that involve complex processes. Expand
Functional and biochemical alterations of the medial frontal cortex in obsessive-compulsive disorder.
TLDR
Hyperactivation of the MFC during high- vs low-conflict conditions in patients with OCD may be a compensatory response to a neuronal abnormality in the region. Expand
Anterior Cingulate Glutamate–Glutamine Levels Predict Symptom Severity in Women With Obsessive–Compulsive Disorder
TLDR
This is the first study to demonstrate gender-specific neurochemical changes in OCD, and the possibility that MRS techniques may be of use in objectively monitoring patient progress and assessing the effectiveness of various treatments is raised. Expand
Right prefrontal repetitive transcranial magnetic stimulation in obsessive-compulsive disorder: a double-blind, placebo-controlled study.
TLDR
Low-frequency rTMS of the right prefrontal cortex failed to produce significant improvement of OCD and was not significantly different from sham treatment. Expand
Consistency and functional specialization in the default mode brain network
TLDR
Three fMRI experiments are performed that demonstrate consistency and specialization in the default mode network and moral dilemma is further shown to evoke regionally specific activity increases of hypothesized functional relevance against rest. Expand
Mapping the self in the brain's default mode network
TLDR
This study examined self-referential and resting-state processes to clarify the extent to which DMN activity was common and distinct between the conditions, and examined the neural network properties of the identified 'core-self' DMN regions-in medial prefrontal cortex, posterior cingulate cortex, and inferior parietal lobule-using dynamic causal modeling. Expand
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