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Altered corticostriatal functional connectivity in obsessive-compulsive disorder.
CONTEXT Neurobiological models of obsessive-compulsive disorder (OCD) emphasize disturbances in the function and connectivity of brain corticostriatal networks, or "loops." Although neuroimagingExpand
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Mapping structural brain alterations in obsessive-compulsive disorder.
BACKGROUND Recent technical developments have made it feasible to comprehensively assess brain anatomy in psychiatric populations. OBJECTIVE To describe the structural brain alterations detected inExpand
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Cerebral lateralization of language in normal left-handed people studied by functional MRI
Objective: To use functional MRI (fMRI) to further define the occurrence of left-hemisphere, bilateral, and right-hemisphere language in a normal left-handed population. Methods: A total of 100Expand
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Functional and biochemical alterations of the medial frontal cortex in obsessive-compulsive disorder.
CONTEXT The medial frontal cortex (MFC), including the dorsal anterior cingulate and the supplementary motor area, is critical for adaptive and inhibitory control of behavior. Abnormally high MFCExpand
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Right prefrontal repetitive transcranial magnetic stimulation in obsessive-compulsive disorder: a double-blind, placebo-controlled study.
OBJECTIVE The efficacy of repetitive transcranial magnetic stimulation (rTMS) of the right prefrontal cortex for patients with obsessive-compulsive disorder (OCD) was studied under double-blind,Expand
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Anterior Cingulate Glutamate–Glutamine Levels Predict Symptom Severity in Women With Obsessive–Compulsive Disorder
Objective: Abnormalities of the anterior cingulate cortex (ACC) have consistently been identified in obsessive–compulsive disorder (OCD), but very few studies have examined the biochemical basis ofExpand
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Time course and functional neuroanatomy of speech segmentation in adults
The present investigation was devoted to unraveling the time-course and brain regions involved in speech segmentation, which is one of the first processes necessary for learning a new language in adults. Expand
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Mapping the self in the brain's default mode network
The brain's default mode network (DMN) has become closely associated with self-referential mental activity, particularly in the resting-state. Expand
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Leuko-araiosis on magnetic resonance imaging and speed of mental processing.
The clinical significance of white matter abnormalities seen in brain imaging studies, termed leuko-araiosis (LA), still remains uncertain. Leuko-araiosis has been associated with a global decline inExpand
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Consistency and functional specialization in the default mode brain network
The notion of a “default mode of brain function” has taken on certain relevance in human neuroimaging studies and in relation to a network of lateral parietal and midline cortical regions that showExpand
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