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Inference of population structure using multilocus genotype data.
- J. Pritchard, M. Stephens, P. Donnelly
- Biology, Medicine
- Genetics
- 30 May 2000
We describe a model-based clustering method for using multilocus genotype data to infer population structure and assign individuals to populations. We assume a model in which there are K populations… Expand
Inference of population structure using multilocus genotype data: dominant markers and null alleles
- D. Falush, M. Stephens, J. Pritchard
- Biology, Medicine
- Molecular ecology notes
- 1 July 2007
Dominant markers such as amplified fragment length polymorphisms (AFLPs) provide an economical way of surveying variation at many loci. However, the uncertainty about the underlying genotypes… Expand
Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies.
- D. Falush, M. Stephens, J. Pritchard
- Biology, Medicine
- Genetics
- 30 July 2003
We describe extensions to the method of Pritchard et al. for inferring population structure from multilocus genotype data. Most importantly, we develop methods that allow for linkage between loci.… Expand
Inferring weak population structure with the assistance of sample group information
- MELISSA J. Hubisz, D. Falush, M. Stephens, J. Pritchard
- Biology, Medicine
- Molecular ecology resources
- 1 September 2009
Genetic clustering algorithms require a certain amount of data to produce informative results. In the common situation that individuals are sampled at several locations, we show how sample group… Expand
A Map of Recent Positive Selection in the Human Genome
- B. Voight, S. Kudaravalli, X. Wen, J. Pritchard
- Biology, Medicine
- PLoS biology
- 1 March 2006
The identification of signals of very recent positive selection provides information about the adaptation of modern humans to local conditions. We report here on a genome-wide scan for signals of… Expand
Association mapping in structured populations.
- J. Pritchard, M. Stephens, N. Rosenberg, P. Donnelly
- Biology, Medicine
- American journal of human genetics
- 1 July 2000
The use, in association studies, of the forthcoming dense genomewide collection of single-nucleotide polymorphisms (SNPs) has been heralded as a potential breakthrough in the study of the genetic… Expand
Inference of Population Splits and Mixtures from Genome-Wide Allele Frequency Data
- Joseph K. Pickrell, J. Pritchard
- Biology, Medicine
- PLoS genetics
- 11 June 2012
Many aspects of the historical relationships between populations in a species are reflected in genetic data. Inferring these relationships from genetic data, however, remains a challenging task. In… Expand
The Genotype-Tissue Expression (GTEx) project
- J. Lonsdale, J. Thomas, +124 authors Helen F Moore
- Medicine, Biology
- Nature Genetics
- 1 May 2013
Genome-wide association studies have identified thousands of loci for common diseases, but, for the majority of these, the mechanisms underlying disease susceptibility remain unknown. Most associated… Expand
Genetic Structure of Human Populations
- N. Rosenberg, J. Pritchard, +4 authors M. Feldman
- Biology, Medicine
- Science
- 20 December 2002
We studied human population structure using genotypes at 377 autosomal microsatellite loci in 1056 individuals from 52 populations. Within-population differences among individuals account for 93 to… Expand
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