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Paraneoplastic limbic encephalitis: neurological symptoms, immunological findings and tumour association in 50 patients.
- S. Gultekin, M. Rosenfeld, R. Voltz, J. Eichen, J. Posner, J. Dalmau
- Brain : a journal of neurology
- 1 July 2000
Paraneoplastic limbic encephalitis (PLE) is a rare disorder characterized by personality changes, irritability, depression, seizures, memory loss and sometimes dementia. The diagnosis is difficult… Expand
Diagnosis and treatment of leptomeningeal metastases from solid tumors: Experience with 90 patients
The clinical findings and response to treatment of leptomeningeal metastases from solid tumors are analyzed in 90 patients treated at Memorial Sloan‐Kettering Cancer Center during the period from… Expand
Anti‐Hu-Associated Paraneoplastic Encephalomyelitis/Sensory Neuronopathy A Clinical Study of 71 Patients
We studied 71 patients with "paraneoplastic" encephalomyelitis, sensory neuronopathy, or both associated with the presence of the anti-Hu antibody in their serum. Most (78%) had small-cell lung… Expand
Paraneoplastic syndromes involving the nervous system.
Paraneoplastic neurologic syndromes are incited by a tumor outside the nervous system that produces a characteristic antigen of the nervous system. An immune response against the ectopic tumor… Expand
Clinical analysis of anti-Ma2-associated encephalitis.
Increasing experience indicates that anti-Ma2-associated encephalitis differs from classical paraneoplastic limbic or brainstem encephalitis, and therefore may be unrecognized. To facilitate its… Expand
Epidural spinal cord compression from metastatic tumor: Diagnosis and treatment
The clinical findings in 130 consecutive cases of spinal cord compression by metastatic extradural tumors were analyzed. These 130 patients were combined with a previous survey of 105 patients to… Expand
Distribution of brain metastases.
The number and site of brain metastases were identified on the computed tomographic scans of 288 patients. There was one brain metastasis in 49%, two in 21%, three in 13%, four in 6%, and five or… Expand
Radiation‐induced dementia in patients cured of brain metastases
When a patient with cancer develops a brain metastasis, death is usually imminent, but aggressive treatment in some patients with limited or no systemic disease yields long-term survival. In such… Expand
Infiltration of the leptomeninges by systemic cancer. A clinical and pathologic study.
Leptomeningeal invasion by systemic cancer was diagnosed clinically or pathologically in 50 patients over four years. All had neurological symptoms referable to tumor seeding the meninges. Clinical… Expand
Brachial plexus lesions in patients with cancer=100 cases
In patients with cancer, brachial plexus signs are usually caused by tumor infiltration or injury from radiation therapy (RT). We analyzed 100 cases of brachial plexopathy to determine which clinical… Expand