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Probiotic Mechanisms of Action
TLDR
Probiotics modes of action focusing on how gut microbes influence the host are explored, with a clear understanding of these mechanisms allowing for appropriate probiotic strain selection for specific applications and may uncover novel probiotic functions.
Sources, isolation, characterisation and evaluation of probiotics
TLDR
There is mounting evidence for a potential role for probiotics in the treatment of allergies and intestinal, liver and metabolic diseases and the ability to examine fully sequenced genomes has accelerated the application of genetic approaches to elucidate the functional roles of probiotics.
Breast Cancer and Its Relationship with the Microbiota
TLDR
Specific characteristics of the human microbiome are identified that may serve to develop novel approaches for risk assessment, prevention and treatment for this disease.
Effects of Probiotics and Synbiotics on Obesity, Insulin Resistance Syndrome, Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease: A Review of Human Clinical Trials
TLDR
The oral intake of probiotics and synbiotics as co-adjuvants for the prevention and treatment of obesity, IRS, type 2 diabetes, T2D and NAFLD is partially supported by the data shown, however, further studies are required to understand the precise mechanism of how Probiotics and Synbiotics affect these metabolic disorders.
Effects of Sweeteners on the Gut Microbiota: A Review of Experimental Studies and Clinical Trials
ABSTRACT The consumption of sugar-free foods is growing because of their low-calorie content and the health concerns about products with high sugar content. Sweeteners that are frequently several
Modulation of immunity and inflammatory gene expression in the gut, in inflammatory diseases of the gut and in the liver by probiotics.
TLDR
A systematic review of the probiotic-mediated modulation of gene expression that is associated with the immune system and inflammation and the regulation of immunity and inflammatory gene expression in the gut, in inflammatory diseases of the gut and in the liver is performed.
Extracellular Matrix Remodeling of Adipose Tissue in Obesity and Metabolic Diseases
TLDR
This review is focused at identifying the putative role of ECM in adipose tissue, describing its structure and components, its main tissue receptors, and how it is affected in obesity, and subsequently the importance of an appropriate ECM remodeling in adiposes tissue expansion to prevent metabolic diseases.
Vitamin D: Classic and Novel Actions
TLDR
In addition to classic actions related to mineral homeostasis, vitamin D has novel actions in cell proliferation and differentiation, regulation of the innate and adaptative immune systems, preventive effects on cardiovascular and neurodegenerative diseases, and even antiaging effects.
The Role of Probiotic Lactic Acid Bacteria and Bifidobacteria in the Prevention and Treatment of Inflammatory Bowel Disease and Other Related Diseases: A Systematic Review of Randomized Human
TLDR
The use of probiotics and/or synbiotics has positive effects in the treatment and maintenance of UC, whereas in CD clear effectiveness has only been shown forsynbiotics.
Human Milk Oligosaccharides and Immune System Development
TLDR
HMOs seem to protect breastfed infants against microbial infections and the protective effect has been found to be exerted through cell signaling and cell-to-cell recognition events, enrichment of the protective gut microbiota, the modulation of microbial adhesion, and the invasion of the infant intestinal mucosa.
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