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An Introduction to the Physiology of Hearing
This book deals with the way that the auditory system processes acoustic signals. The current edition has been thoroughly revised to reflect the progress that has been made since the previousExpand
Cross-links between stereocilia in the guinea pig organ of Corti, and their possible relation to sensory transduction
TLDR
Hair cells of the guinea pig cochlea were preserved by fixing in glutaraldehyde without the use of osmium to explain the V shape of the rows of stereocilia on outer hair cells, and a membrane roughness was seen, particularly pronounced in the region of the stereocilium which gives rise to the cross-links. Expand
Morphology of the monotreme organ of corti and macula lagena
TLDR
The organ of Corti and macula lagena were studied by scanning and transmission electron microscopy in two species of monotreme, the platypus and echidna, with signs of a vestibular epithelium and a systematic change in orientation across the cochlear duct. Expand
Psychophysical frequency resolution in the cat as determined by simultaneous masking and its relation to auditory-nerve resolution.
  • J. Pickles
  • Physics, Medicine
  • The Journal of the Acoustical Society of America
  • 1 December 1979
TLDR
The results suggest that the critical band as measured by simultaneous masking is not a close relation of the frequency-threshold curve of auditory-nerve fibers, but that the psychophysical tuning curve possibly may be. Expand
Mechanoelectrical transduction by hair cells
TLDR
Hair cells of the inner ear are specialized columnar epithelial cells, with an array of modified microvilli or stereocilia on their apical surface, interconnected by a series of linkages. Expand
The expression of fibroblast growth factors and their receptors in the embryonic and neonatal mouse inner ear
  • J. Pickles
  • Medicine, Biology
  • Hearing Research
  • 1 May 2001
TLDR
It is suggested that the different FGF receptors and ligands are expressed in a spatially coordinated pattern, to selectively program cochlear development. Expand
Normal critical bands in the cat.
  • J. Pickles
  • Medicine
  • Acta oto-laryngologica
  • 1 September 1975
TLDR
The measured critical bandwidth was greater than previously published values of the effective bandwidths of single fibres of the auditory nerve and does not fit in with the commonly accepted theory that the critical band represents the resolution of the cochlea. Expand
A model for the mechanics of the stereociliar bundle on acousticolateral hair cells
  • J. Pickles
  • Physics, Medicine
  • Hearing Research
  • 1 August 1993
TLDR
Comparison of the results with the measured mechanical properties of hair bundles suggests that in the bullfrog sacculus the stiffness of a side link and a tip link are related to the rootlet's contribution to the stiffnessof a stereocilium to deflection in approximately the ratio > or = 400:100:1. Expand
The development of links between stereocilia in hair cells of the chick basilar papilla
TLDR
It is suggested that tip links are a specialisation of the links which join immature stereocilia laterally near their tips, and that the orientation of tip links, parallel to the hair cell axis of bilateral symmetry, is produced by the gradient in growth of the stereOCilia. Expand
Expression of Ephs and ephrins in developing mouse inner ear
  • J. Pickles
  • Medicine, Biology
  • Hearing Research
  • 1 April 2003
TLDR
The results suggest that the Ephs and ephrins are likely to play a part in the differentiation of the structures of the inner ear, and show which Ephingredients are most likely toPlay important roles in the different structures. Expand
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