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The amount of skeletal mass acquired during adolescence is one of the most important determinants for the risk of postmenopausal and involutional osteoporosis. In both sexes, a large variance in bone(More)
Stature, bone size, and bone mass are interrelated traits with high heritability, but the major genes that govern these phenotypes remain unknown. Independent genomewide quantitative-trait locus(More)
Fracture of the proximal femur is the most dramatic clinical sequela of osteoporosis [1, 2]. It is associated with a high mortality rate, need for long-term medical care, and prolonged disability(More)