• Publications
  • Influence
Effect of carbonyl cyanide m-chlorophenylhydrazone (CCCP) on the dimerization of lipoprotein lipase.
  • J. Park, S. Lee, +5 authors H. Kim
  • Chemistry, Medicine
  • Biochimica et biophysica acta
  • 21 January 1997
Lipoprotein lipase (LPL), an enzyme playing the central role in triglyceride metabolism, is a glycoprotein and a homodimer of identical subunits. Dimerization and proper processing of oligosaccharideExpand
Generation of strand breaks and formation of 8-hydroxy-2'-deoxyguanosine in DNA by a Thiol/Fe3+/O2-catalyzed oxidation system.
  • J. Park, R. Floyd
  • Chemistry, Medicine
  • Archives of biochemistry and biophysics
  • 1 July 1994
Strand breaks are produced in pBluescript plasmid DNA by a metal-catalyzed oxidation system composed of Fe3+, O2, and a thiol as an electron donor. Formation of 8-hydroxy-2'-deoxyguanosine (8-OH-dG)Expand
Pulmonary damage by Vibrio vulnificus cytolysin.
Vibrio vulnificus is an estuarine bacterium that causes septicemia and serious wound infection. Cytolysin produced by V. vulnificus has been incriminated as one of the important virulenceExpand
Strain energy release in ceramic-to-metal joints by ductile metal interlayers
Abstract We present analytical solutions for thermal strain energy in ceramic-to-metal joints where the coefficient of thermal expansion (CTE) of the interlayer is significantly larger than that ofExpand
Transnitrosation as a predominant mechanism in the hypotensive effect of S-nitrosoglutathione.
S-Nitrosoglutathione, a possible intermediate in the pharmacological mechanisms of many vasodilators, undergoes hemolysis at pH 7.4 and 37 degrees C to give oxidized glutathione and nitric oxide withExpand
Translocation of recombinant p47phox cytosolic component of the phagocyte oxidase by in vitro phosphorylation.
  • J. Park, S. Ahn
  • Chemistry, Medicine
  • Biochemical and biophysical research…
  • 15 June 1995
Activation of superoxide-generating NADPH oxidase system of human neutrophils involves phosphorylation-dependent translocation of p47phox and other cytosolic components to the plasma membrane. InExpand
Attenuation of p47phox and p67phox membrane translocation as the inhibitory mechanism of S-nitrosothiol on the respiratory burst oxidase in human neutrophils.
  • J. Park
  • Chemistry, Medicine
  • Biochemical and biophysical research…
  • 7 March 1996
The effect of the S-nitrosothiol (RSNO) on the activation of NADPH oxidase in human neutrophils was studied using an in vitro translocation system in which an anionic amphiphil, such as sodiumExpand
Inhibitory mechanism of Ca2+ on the hemolysis caused by Vibrio vulnificus cytolysin.
Calcium in millimolar concentrations protected mouse erythrocytes from hemolysis caused by Vibrio vulnificus cytolysin without affecting the release of intracellular K+ from the cells. This effectExpand
Phosphatidic acid-induced translocation of cytosolic components in a cell-free system of NADPH oxidase: mechanism of activation and effect of diacylglycerol.
  • J. Park
  • Chemistry, Medicine
  • Biochemical and biophysical research…
  • 24 December 1996
The translocation of the cytosolic components p47(phox) and p67(phox) to the plasma membrane and O-2 generation of the NADPH oxidase from human neutrophils can be elicited with phosphatidic acid (PA)Expand
Dual role of S-nitrosocaptopril as an inhibitor of angiotensin-converting enzyme and a nitroso group carrier.
  • J. Park
  • Chemistry, Medicine
  • Biochemical and biophysical research…
  • 30 November 1992
The S-nitroso derivatives of captopril can act as an inhibitor of an angiotensin-converting enzyme in the presence of thiol such as glutathione. S-Nitrosocaptopril also rapidly transfers its nitrosoExpand