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Overcoming muscle atrophy in a hibernating mammal despite prolonged disuse in dormancy: Proteomic and molecular assessment
Prolonged disuse of skeletal muscle causes significant loss of myofibrillar contents, muscle tension, and locomotory capacity. However, hibernating mammals like bats appear to deviate from thisExpand
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Double‐stranded RNA mediates interferon regulatory factor 3 activation and interleukin‐6 production by engaging Toll‐like receptor 3 in human brain astrocytes
Toll‐like receptor 3 (TLR3) participates in the innate immune response by recognizing viral pathogens. In this study, human brain astrocytes were found to constitutively express TLR3, and thisExpand
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Induction of proinflammatory mediators requires activation of the TRAF, NIK, IKK and NF‐κB signal transduction pathway in astrocytes infected with Escherichia coli
  • J. Kim, Y. Oh, +8 authors I-H Choi
  • Biology, Medicine
  • Clinical and experimental immunology
  • 1 June 2005
Escherichia coli is associated with inflammation in the brain. To investigate whether astrocytes are involved in E. coil‐induced inflammation, we assessed the levels of expression of proinflammatoryExpand
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Differential Expression, Shedding, Cytokine Regulation and Function of TNFR1 and TNFR2 in Human Fetal Astrocytes
Tumor necrosis factor (TNF)-α induces pleiotropic cellular effects through a 55kDa, type 1 receptor (TNFR1) and a 75kDa type 2 receptor (TNFR2). Moreover, it participates in the pathogenesis ofExpand
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Rapid differentiation of Candida albicans from other Candida species using its unique germ tube formation at 39° C
In this study, we found that no Candida species other than C. albicans is able to form germ tubes at 39° C in serum-free YEPD (1% (w/v) yeast extract, 2% (w/v) peptone and 2% (w/v) dextrose) media,Expand
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Salmonella enterica serovar London infections associated with consumption of infant formula.
Epidemiologic studies were conducted on 31 cases of Salmonella group E infection detected in 2000 through a laboratory-based pathogen surveillance in Gangwon Province, Korea. Data were collected onExpand
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Immunological features of macrophages induced by various morphological structures of Candida albicans.
Candida albicans is a dimorphic fungus that commensally colonizes human mucosal surfaces. The aim of this study was to assess the role of different C. albicans morphologies in inducing patternExpand
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Effects of Cytokines on VEGF Expression and Secretion by Human First Trimester Trophoblast Cell Line
PROBLEM: The mechanism through which vascular endothelial growth factor (VEGF) regulation occurs at the feto‐maternal interface is poorly understood. The aim of this study was to investigate theExpand
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Effect of DNA topology on plasmid DNA repair in vivo
Escherichia coli nucleotide excision repair (NER) is responsible for removing bulky DNA adducts by dual incisions of the UvrABC endonuclease. Although the activity of the UvrAB complex which canExpand
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The Influence of Urinary Catheter Materials on Forming Biofilms of Microorganisms
Biofilms are commonly associated with an increased risk of catheter-associated infection. To study the efficacy of materials designed to reduce biofilm formation, microbial biofilms on clinicallyExpand
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