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Metabolic profile and cardiovascular risk patterns of an Indian tribe living in the Amazon Region of Brazil.
TLDR
The high rates of cardiovascular risk factors found among these Indians point to there being a high-risk group to develop diabetes and cardiovascular diseases, and to reduce this risk they need to receive preventive interventions. Expand
Gene frequencies of the HPA‐15 (Gov) platelet alloantigen system in Brazilians
Summary.  The HPA‐15 (Gov) alloantigen is a biallelic co‐dominant system on human platelets, and its allele HPA‐15a and HPA‐15b differ by an A→C single nucleotide polymorphism at nucleotide 2108 ofExpand
A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans.
TLDR
This is the first report of a common functional variant exclusive to Native American and descent populations, which is a major determinant of HDL-C levels and may have contributed to the adaptive evolution of Native American populations. Expand
Selectivity of human T lymphotropic virus type-1 (HTLV-1) and HTLV-2 infection among different populations in Brazil.
TLDR
The selectivity of these retroviral infections in particular groups is emphasized, as well as the need for HTLV-1/2 screening of all blood donors in Brazil as a public health measure. Expand
High prevalence of type 2 diabetes mellitus in Xavante Indians from Mato Grosso, Brazil.
TLDR
The high prevalence of diabetes and obesity in Xavante is likely related to their recent change in food habits and physical activities and could increase dramatically in the future if no preventive actions are adopted. Expand
Serum total homocysteine levels and the prevalence of folic acid deficiency and C677T mutation at the MTHFR gene in an indigenous population of Amazonia: the relationship of homocysteine with other
TLDR
High rates of cardiovascular risk factors were discovered and C667T mutation and folic acid deficiency can explain, at least in part, the observed hyperhomocysteinemia. Expand
Allelic polymorphisms of human Fcγ receptor IIa and Fcγ receptor IIIb among distinct groups in Brazil
TLDR
This work has shown that the FcγRIIA gene is expressed in two polymorphic forms, R131 and H131, which differ by the replacement of histidine by arginine at position 131. Expand
Prevalence of metabolic syndrome in the Brazilian Xavante indigenous population
TLDR
The high prevalence of MS in the Xavante Indians is mainly due to the increased prevalence of weight excess that resulted from an intense change in their life-style, in a short period of time in a population with a genetic predisposition. Expand
HNA‐3 gene frequencies in Brazilians and a new polymerase chain reaction–restriction fragment length polymorphism method for HNA‐3a/3b genotyping
TLDR
This study determined the frequency of the HNA‐3 alleles in Brazilians and found that anti‐HNA‐ 3 are involved in severe transfusion‐related acute lung injury reactions and in neonatal alloimmune neutropenia. Expand
Risk factors for heart disease.
TLDR
Risk factors are traits and lifestyle habits that increase the chance of having a disease and can be controlled, such as your age, gender and family history. Expand
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