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Altered expression of synapse and glutamate related genes in post-mortem hippocampus of depressed subjects.
TLDR
The genetic profile of micro-dissected subfields of post-mortem hippocampus from subjects diagnosed with MDD and comparison subjects matched for sex, race and age are examined, providing new evidence that disruption of synaptic and glutamatergic signalling pathways contribute to the pathophysiology underlying MDD.
Self-esteem deficits and suicidal tendencies among adolescents.
TLDR
Low self-esteem was closely related to feelings of depression, hopelessness, and suicidal tendencies and added to the understanding of suicidal ideation beyond what could be explained by depression and hopelessness.
Suicidal Ideation in Adolescent Psychiatric Inpatients as Associated With Depression and Attachment Relationships
TLDR
Prevention and treatment efforts may focus on mother-adolescent attachment and peer attachment (particularly in girls) to reduce risk for depression and suicidal ideation.
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